Twins vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 2:12 a.m.

On Saturday in MLB, the Minnesota Twins are playing the Arizona Diamondbacks.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs Diamondbacks Game Info

• Minnesota Twins (65-82) vs. Arizona Diamondbacks (73-75)
• Date: Saturday, September 13, 2025
• Time: 7:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and ARID

Twins vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-136) | ARI: (+116)
• Spread: MIN: -1.5 (+150) | ARI: +1.5 (-182)
• Total: 8.5 -- Over: (+102) | Under: (-124)

Twins vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 13-8, 3.32 ERA vs Ryne Nelson (Diamondbacks) - 7-3, 3.48 ERA

The probable pitchers are Joe Ryan (13-8) for the Twins and Ryne Nelson (7-3) for the Diamondbacks. Ryan and his team are 12-14-0 ATS this season when he starts. Ryan's team has been victorious in 52.4% of the games he's started as the moneyline favorite with a record of 11-10. The Diamondbacks have an 11-9-0 record against the spread in Nelson's starts. The Diamondbacks have a 4-4 record in Nelson's eight starts this season when they were the moneyline underdog.

Twins vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (52.6%)

Twins vs Diamondbacks Moneyline

• Arizona is a +116 underdog on the moneyline, while Minnesota is a -136 favorite at home.

Twins vs Diamondbacks Spread

• The Twins are hosting the Diamondbacks and are favored by 1.5 runs (+150 to cover) on the runline. Arizona is -182 to cover.

Twins vs Diamondbacks Over/Under

• An over/under of 8.5 has been set for Twins-Diamondbacks on Sept. 13, with the over being +102 and the under -124.

Bet on Minnesota Twins vs. Arizona Diamondbacks on FanDuel today!

Twins vs Diamondbacks Betting Trends

• The Twins have been favorites in 84 games this season and have come away with the win 40 times (47.6%) in those contests.
• Minnesota has a record of 22-18 in contests when oddsmakers favor them by -136 or more on the moneyline.
• The Twins and their opponents have gone over the total this season in 68 of their 142 opportunities.
• The Twins have an against the spread mark of 69-73-0 in 142 games with a line this season.
• The Diamondbacks have won 47.5% of the games this season they were the moneyline underdog (29-32).
• Arizona has gone 16-14 when it has played as a moneyline underdog with odds of +116 or longer (53.3%).
• The Diamondbacks have played in 144 games with an over/under set, and have combined with opponents to go over the total 72 times (72-66-6).
• The Diamondbacks have a 71-73-0 record ATS this season.

Twins Player Leaders

• Byron Buxton has 118 hits and an OBP of .338, both of which lead Minnesota hitters this season. He has a .274 batting average and a slugging percentage of .565.
• Among all qualifying batters in MLB, his batting average ranks 35th, his on-base percentage ranks 54th, and he is fourth in slugging.
• Buxton hopes to build on a five-game hitting streak in this matchup. In his last five games he is batting .375 with a triple, two home runs, a walk and four RBIs.
• Trevor Larnach has hit 16 homers this season while driving in 58 runs. He's batting .254 this season and slugging .405 with an on-base percentage of .326.
• His batting average ranks 88th among qualified players, his on-base percentage 82nd, and his slugging percentage 97th.
• Brooks Lee is batting .237 with a .369 slugging percentage and 58 RBI this year.
• Kody Clemens is batting .213 with a .282 OBP and 48 RBI for Minnesota this season.

Diamondbacks Player Leaders

• Geraldo Perdomo has accumulated a team-high OBP (.386) and slugging percentage (.455). He's batting .285.
• Including all the qualifying hitters in the big leagues, his batting average puts him 17th, his on-base percentage ranks sixth, and he is 52nd in slugging.
• Perdomo takes a three-game hitting streak into this matchup. During his last five outings he is hitting .235 with two home runs, four walks and four RBIs.
• Corbin Carroll's 133 hits lead his team. He has a batting average of .256 while slugging .546 with an on-base percentage of .334.
• Including all qualified players, he is 83rd in batting average, 62nd in on-base percentage and sixth in slugging percentage.
• Ketel Marte has 22 doubles, 25 home runs and 63 walks while batting .281.
• Gabriel Moreno is hitting .290 with 11 doubles, a triple, nine home runs and 20 walks.

Twins vs Diamondbacks Head to Head

• 9/12/2025: 9-8 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/27/2024: 13-6 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/26/2024: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/25/2024: 5-4 ARI (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/5/2023: 12-1 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/4/2023: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/19/2022: 7-1 ARI (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/18/2022: 11-1 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/17/2022: 7-2 ARI (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)

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