Twins vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for March 29

Odds updated as of 2:11 p.m.
The Minnesota Twins are among the MLB squads busy on Saturday, up against the St. Louis Cardinals.
All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.
Twins vs Cardinals Game Info
- Minnesota Twins (0-1) vs. St. Louis Cardinals (1-0)
- Date: Saturday, March 29, 2025
- Time: 2:15 p.m. ET
- Venue: Busch Stadium -- St. Louis, Missouri
- Coverage: Fox Sports 1, FDSMW, and MNNT
Twins vs Cardinals Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: MIN: (-112) | STL: (-104)
- Spread: MIN: -1.5 (+158) | STL: +1.5 (-192)
- Total: 7.5 -- Over: (-115) | Under: (-105)
Twins vs Cardinals Probable Starting Pitchers
Probable Pitchers: Joe Ryan (Twins) - 0-0, 0.00 ERA vs Erick Fedde (Cardinals) - 0-0, 0.00 ERA
The Twins will look to Joe Ryan against the Cardinals and Erick Fedde. Ryan and his team were 8-15-0 against the spread when he pitched last season. Ryan and his team won as favorites in 47.6% of his 21 appearances last season with a moneyline. Last season Fedde and his team went 19-12-0 against the spread when he pitched. Fedde and his team went 9-17 in games he appeared in when they were the underdog on the moneyline a season ago.
Twins vs Cardinals Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (52.6%)
Twins vs Cardinals Moneyline
- Minnesota is a -112 favorite on the moneyline, while St. Louis is a -104 underdog at home.
Twins vs Cardinals Spread
- The Twins are at the Cardinals and are favored by 1.5 runs on the spread. The Twins are +158 to cover the runline, with the Cardinals being -192.
Twins vs Cardinals Over/Under
- A total of 7.5 runs has been set for the Twins-Cardinals contest on March 29, with the over available at -115 and the under at -105.
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Twins vs Cardinals Betting Trends
- The Twins were victorious in 62, or 56.9%, of the 109 contests they were chosen as favorites last season.
- Last season Minnesota came away with a win 61 times in 107 chances when named as a favorite of at least -112 or shorter on the moneyline.
- The Twins and their opponents hit the over in 80 of their 158 games with a total last season.
- The Cardinals went 40-42 in games they were listed as the moneyline underdog last season (winning 48.8% of those games).
- When playing as a moneyline underdog with odds of -104 or longer last year, St. Louis went 39-36 (52%).
- The Cardinals played in 157 games with a set over/under last season, and combined with their opponents to go over the total 72 times (72-83-2).
Twins Player Leaders
- Willi Castro collected 138 hits, posted an OBP of .331 and a .385 SLG last season.
- Carlos Correa slashed .310/.388/.517 and finished with an OPS of .905.
- Last season, Ryan Jeffers finished with 21 home runs, 64 RBI and a batting average of .226 last season.
- Byron Buxton slashed .279/.335/.524 and finished with an OPS of .859.
Cardinals Player Leaders
- Brendan Donovan accumulated a .342 on-base percentage and a .417 slugging percentage last season.
- Alec Burleson had 147 hits with a .269 batting average.
- Masyn Winn hit .267 with 32 doubles, five triples, 15 home runs and 41 walks a season ago.
- Nolan Arenado hit .272 with 23 doubles, 16 home runs and 44 walks.
Twins vs Cardinals Head to Head
- 3/27/2025: 5-3 STL (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
- 8/25/2024: 3-2 STL (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
- 8/24/2024: 6-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
- 8/23/2024: 6-1 STL (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
- 8/3/2023: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
- 8/2/2023: 7-3 STL (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
- 8/1/2023: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
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