Twins vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for May 16

Odds updated as of 7:11 a.m.

The Friday schedule in MLB includes a matchup between the Minnesota Twins and the Milwaukee Brewers.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Twins vs Brewers Game Info

• Minnesota Twins (24-20) vs. Milwaukee Brewers (21-23)
• Date: Friday, May 16, 2025
• Time: 8:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and MNNT

Twins vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-110) | MIL: (-106)
• Spread: MIN: -1.5 (+146) | MIL: +1.5 (-178)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Twins vs Brewers Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 3-2, 2.74 ERA vs Chad Patrick (Brewers) - 2-3, 3.19 ERA

The probable pitchers are Joe Ryan (3-2) for the Twins and Chad Patrick (2-3) for the Brewers. Ryan and his team have a record of 3-5-0 against the spread when he starts. Ryan's team has won 40% of his starts when they are favored on the moneyline (2-3). The Brewers have a 4-3-0 record against the spread in Patrick's starts. The Brewers were the underdog on the moneyline for two Patrick starts this season -- they lost both.

Twins vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.2%)

Twins vs Brewers Moneyline

• The Twins vs Brewers moneyline has Minnesota as a -110 favorite, while Milwaukee is a -106 underdog at home.

Twins vs Brewers Spread

• The Twins are 1.5-run road favorites on the runline against the Brewers. The Twins are +146 to cover, and the Brewers are -178.

Twins vs Brewers Over/Under

• The Twins-Brewers game on May 16 has been given an over/under of 7.5 runs. The over is set at -120 and the under at -102.

Bet on Minnesota Twins vs. Milwaukee Brewers on FanDuel today!

Twins vs Brewers Betting Trends

• The Twins have won in 15, or 55.6%, of the 27 contests they have been named as odds-on favorites in this year.
• This season Minnesota has come away with a win 15 times in 27 chances when named as a favorite of at least -110 on the moneyline.
• The Twins and their opponents have gone over in 16 of their 43 games with a total set by sportsbooks this season.
• The Twins have an against the spread mark of 24-19-0 in 43 games with a line this season.
• The Brewers have been the moneyline underdog 21 total times this season. They've gone 5-16 in those games.
• Milwaukee has a 4-16 record (winning just 20% of its games) when it has played as a moneyline underdog of -106 or longer.
• In the 43 games oddsmakers have set an over/under for the Brewers, they have combined with opponents to go over the total 17 times (17-25-1).
• The Brewers have covered 53.5% of their games this season, going 23-20-0 ATS.

Twins Player Leaders

• Byron Buxton has 41 hits to go with a slugging percentage of .522, both of which are best among Minnesota hitters this season. He has a .261 batting average and an on-base percentage of .312.
• Among qualifying hitters in the majors, he is 70th in batting average, 103rd in on-base percentage, and 21st in slugging.
• Buxton will look for his third straight game with a hit in this contest. In his last five games he is hitting .118 with a home run, three walks and two RBIs.
• Trevor Larnach has 39 hits this season and a team-best OBP of .318. He's batting .244 and slugging .406.
• His batting average is 101st among qualified players, his on-base percentage 95th, and his slugging percentage 88th.
• Ty France has collected 39 base hits, an OBP of .316 and a slugging percentage of .361 this season.
• Harrison Bader has four home runs, 18 RBI and a batting average of .300 this season.
• Bader heads into this game on a five-game hitting streak. In his last five games he is hitting .400 with two doubles, a walk and two RBIs.

Brewers Player Leaders

• Jackson Chourio has racked up a team-best .457 slugging percentage. He's batting .258 with an on-base percentage of .276.
• Including all the qualified hitters in the majors, his batting average puts him 75th, his on-base percentage ranks 140th, and he is 56th in slugging.
• Brice Turang is batting .289 with three doubles, three home runs and 19 walks. He's slugging .368 with an on-base percentage of .368.
• He is 35th in batting average, 37th in on-base percentage and 120th in slugging percentage in the big leagues.
• William Contreras has three doubles, four home runs and 25 walks while batting .238.
• Rhys Hoskins leads his team with 38 hits and a .396 OBP.

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