Tigers vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 18

Odds updated as of 2:11 a.m.

The Detroit Tigers are among the MLB squads playing on Monday, versus the Cleveland Guardians.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Tigers vs Guardians Game Info

• Detroit Tigers (20-27) vs. Cleveland Guardians (26-22)
• Date: Monday, May 18, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: Fox Sports 1, DSN, and CleGuardians.TV

Tigers vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-154) | CLE: (+130)
• Spread: DET: -1.5 (+134) | CLE: +1.5 (-162)
• Total: 8.5 -- Over: (+100) | Under: (-122)

Tigers vs Guardians Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Tigers) - 2-2, 4.32 ERA vs Slade Cecconi (Guardians) - 2-4, 5.60 ERA

The probable starters are Framber Valdez (2-2) for the Tigers and Slade Cecconi (2-4) for the Guardians. Valdez and his team are 5-4-0 ATS this season when he starts. Valdez's team is 2-3 this season when he starts and they are the moneyline favorite. The Guardians are 3-6-0 ATS in Cecconi's nine starts that had a set spread. The Guardians are 2-5 in Cecconi's seven starts this season that they were the moneyline underdog.

Tigers vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (65%)

Tigers vs Guardians Moneyline

• Detroit is the favorite, -154 on the moneyline, while Cleveland is a +130 underdog on the road.

Tigers vs Guardians Spread

• The Tigers are hosting the Guardians and are favored by 1.5 runs (+134 to cover) on the runline. Cleveland is -162 to cover.

Tigers vs Guardians Over/Under

• The over/under for Tigers-Guardians on May 18 is 8.5. The over is +100, and the under is -122.

Bet on Detroit Tigers vs. Cleveland Guardians on FanDuel today!

Tigers vs Guardians Betting Trends

• The Tigers have been victorious in 13, or 52%, of the 25 contests they have been chosen as favorites in this season.
• This season Detroit has been victorious four times in seven chances when named as a favorite of at least -154 on the moneyline.
• The Tigers' games have gone over the total in 21 of their 47 opportunities.
• The Tigers are 23-24-0 against the spread in their 47 games with a line set by sportsbooks this season.
• The Guardians have won 52.4% of the games this season they were the moneyline underdog (11-10).
• Cleveland has gone 4-4 when playing as a moneyline underdog with odds of +130 or longer (50%).
• The Guardians have had an over/under set by bookmakers 46 times, and have combined with opponents to go over the total in 25 of those games (25-21-0).
• The Guardians have covered 54.3% of their games this season, going 25-21-0 ATS.

Tigers Player Leaders

• Kevin McGonigle is hitting .290 with 12 doubles, two triples, two home runs and 27 walks. He has an on-base percentage of .394 while slugging .420.
• He ranks 28th in batting average, 13th in on-base percentage, and 72nd in slugging among all qualified hitters in the majors.
• McGonigle will look for his third straight game with a hit in this contest. In his last five games he is batting .211 with three walks.
• Riley Greene is slashing .320/.410/.473 this season and leads the Tigers with an OPS of .884.
• Among all qualifying hitters, he is seventh in batting average, fourth in on-base percentage and 40th in slugging percentage.
• Dillon Dingler leads Detroit in total hits (37) this season, and 17 of those have gone for extra bases.
• Matt Vierling has been key for Detroit with 23 hits, an OBP of .280 plus a slugging percentage of .369.

Guardians Player Leaders

• Jose Ramirez is hitting .229 with nine doubles, seven home runs and 35 walks. He's slugging .400 with an on-base percentage of .358.
• Including all qualifying hitters in the majors, he ranks 128th in batting average, 46th in on-base percentage and 87th in slugging percentage.
• Ramirez hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .353 with a double, a home run, four walks and three RBIs.
• Chase DeLauter paces his team with a .367 OBP, and has a club-leading .494 slugging percentage. He has a batting average of .282.
• He is currently 35th in batting average, 39th in on-base percentage and 29th in slugging percentage among all qualified hitters.
• Brayan Rocchio is hitting .285 with five doubles, four home runs and 16 walks.
• Angel Martinez's 38 hits lead his team.

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