Spurs vs. 76ers Prediction, Odds, Picks, Best Bets for March 21

Spurs vs. 76ers Game Info

• Date: Friday, March 21, 2025
• Time: 8 p.m. ET
• Venue: Frost Bank Center -- San Antonio, Texas
• Coverage: FDSSW and NBCS-PH

The San Antonio Spurs (29-39) take the court against the Philadelphia 76ers (23-46) as 6-point favorites on Friday, March 21, 2025 at 8 p.m. ET on FDSSW and NBCS-PH. The matchup has an over/under of 235.5.

Spurs vs. 76ers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Spurs vs. 76ers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Spurs win (63.6%)

Spurs vs. 76ers Betting Trends

• The Spurs are 30-38-0 against the spread this season.
• The 76ers have 26 wins against the spread in 69 games this year.
• Games involving the Spurs have hit the over 38 times out of 69 chances this season.
• 76ers games this season have gone over the total in 40 of 69 opportunities (58%).
• In home games, San Antonio has a better record against the spread (17-18-0) compared to its ATS record in road games (13-20-0).
• When playing at home, the Spurs go over the over/under 54.3% of the time (19 of 35 games). They hit the over more often in away games, topping the total in 57.6% of games (19 of 33).
• In 2024-25 against the spread, Philadelphia has a lower winning percentage at home (.324, 11-23-0 record) than on the road (.429, 15-20-0).
• Looking at the over/under, 76ers games have gone over less frequently at home (18 of 34, 52.9%) than away (22 of 35, 62.9%).

Spurs Leaders

• De'Aaron Fox is averaging 23.5 points, 4.8 boards and 6.3 assists. At the other end, he averages 1.5 steals (ninth in league) and 0.4 blocked shots.
• Victor Wembanyama averages 24.3 points, 11 boards and 3.7 assists, shooting 47.6% from the field and 35.2% from beyond the arc, with 3.1 made 3-pointers per contest.
• Chris Paul's numbers on the season are 8.8 points, 3.7 boards and 7.8 assists per game, shooting 42.1% from the field and 37.7% from beyond the arc, with an average of 1.7 made 3-pointers.
• Stephon Castle averages 14 points, 3.2 rebounds and 3.5 assists, shooting 42.8% from the field and 28.9% from downtown, with 1.2 made treys per game.
• Devin Vassell is averaging 16 points, 3.9 rebounds and 2.9 assists. Defensively, he averages 1.3 steals and 0.6 blocked shots.

76ers Leaders

• Quentin Grimes is averaging 13.4 points, 4.2 rebounds and 2.6 assists for the 76ers.
• The 76ers are getting 10.5 points, 5.5 rebounds and 2 assists per game from Guerschon Yabusele.
• The 76ers receive 16.2 points per game from Paul George, plus 5.3 boards and 4.3 assists.
• Joel Embiid's numbers on the season are 23.8 points, 8.2 boards and 4.5 assists per game. He is sinking 44.4% of his shots from the floor and 29.9% from beyond the arc, with an average of 1.2 treys.
• The 76ers are getting 6.6 points, 2.4 rebounds and 1.2 assists per game from Ricky Council IV.

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