Seahawks vs Chiefs Prediction, Odds, Picks, Best Bets for NFL Week 7

The NFL slate on Sunday includes the Seattle Seahawks facing the Kansas City Chiefs.
All the information you need is below, in order to make a smart bet on this matchup at FanDuel Sportsbook.
Seahawks vs Chiefs Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Chiefs win (56.4%)
Seahawks vs Chiefs Point Spread
The Seahawks are 2.5-point favorites against the Chiefs. The Seahawks are -122 to cover the spread, while the Chiefs are +100 to cover as a 2.5-point underdog.
Seahawks vs Chiefs Over/Under
The Seahawks-Chiefs game on Oct. 25 has been given an over/under of 42.5 points. The over is -110 and the under is -110.
Seahawks vs Chiefs Moneyline
Kansas City is the underdog, +124 on the moneyline, while Seattle is a -146 favorite at home.
Seahawks vs Chiefs Betting Trends
- Seattle has posted one win against the spread this year.
- The Seahawks have won once ATS (1-4-1) as a 2.5-point favorite or more this year.
- There have been three Seahawks games (out of six) that hit the over this season.
- The Chiefs have beaten the spread three times in five games.
- Two of the Chiefs' five games in 2026 have gone over the point total.
Check out even more in-depth Seahawks vs. Chiefs analysis on FanDuel Research.
Seahawks vs Chiefs Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: SEA: (-146) | KC: (+124)
- Spread: SEA: -2.5 (-122) | KC: +2.5 (100)
- Total: 42.5 -- Over: (-110) | Under: (-110)
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