Red Sox vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 3:12 p.m.

Saturday's slate in the MLB includes a matchup between the Boston Red Sox and the Detroit Tigers.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Tigers Game Info

• Boston Red Sox (88-72) vs. Detroit Tigers (86-74)
• Date: Saturday, September 27, 2025
• Time: 4:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: NESN and FDSDET

Red Sox vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-116) | DET: (-102)
• Spread: BOS: +1.5 (-200) | DET: -1.5 (+164)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Red Sox vs Tigers Probable Starting Pitchers

Probable Pitchers: Connelly Early (Red Sox) - 1-1, 1.88 ERA vs Keider Montero (Tigers) - 5-3, 4.48 ERA

The Red Sox will look to Connelly Early (1-1) against the Tigers and Keider Montero (5-3). Early and his team have a record of 1-2-0 against the spread when he starts. Early's team is 0-2 this season when he starts and they're favored on the moneyline. The Tigers have a 7-3-0 ATS record in Montero's 10 starts with a set spread. The Tigers have been the moneyline underdog in three of Montero's starts this season, and they went 1-2 in those matchups.

Red Sox vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (58.6%)

Red Sox vs Tigers Moneyline

• Looking at the moneyline for Tigers-Red Sox, Detroit is the underdog at -102, and Boston is -116 playing at home.

Red Sox vs Tigers Spread

• The Tigers are 1.5-run favorites against the spread for this matchup with the Red Sox. The Tigers are +164 to cover, while the Red Sox are -200 to cover as a 1.5-run underdog on the runline.

Red Sox vs Tigers Over/Under

• A total of 8.5 runs has been set for the Red Sox-Tigers game on Sept. 27, with the over available at -110 and the under at -110.

Bet on Boston Red Sox vs. Detroit Tigers on FanDuel today!

Red Sox vs Tigers Betting Trends

• The Red Sox have come away with 58 wins in the 100 contests they have been listed as the favorites in this season.
• This season Boston has been victorious 55 times in 93 chances when named as a favorite of at least -116 on the moneyline.
• The Red Sox and their opponents have hit the over in 74 of their 159 games with a total set by oddsmakers this season.
• The Red Sox are 85-74-0 against the spread in their 159 games with a line set by sportsbooks this season.
• The Tigers have won 48.8% of the games this season they were the underdog on the moneyline (21-22).
• Detroit has a record of 15-20 when it has played as a moneyline underdog with odds of -102 or longer (42.9%).
• In the 153 games bookmakers have set an over/under for the Tigers, they have combined with opponents to go over the total 78 times (78-69-6).
• The Tigers have a 71-82-0 record against the spread this season.

Red Sox Player Leaders

• Jarren Duran is batting .257 with 40 doubles, 13 triples, 16 home runs and 60 walks. He has an on-base percentage of .333 while slugging .442.
• Among all qualifying hitters in the majors, his batting average ranks 77th, his on-base percentage ranks 65th, and he is 63rd in slugging.
• Duran hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .150 with a double, two walks and an RBI.
• Trevor Story leads Boston in slugging percentage (.436) thanks to 54 extra-base hits. He's batting .265 with an on-base percentage of .310.
• He is 49th in batting average, 109th in on-base percentage and 70th in slugging among qualified hitters.
• Alex Bregman leads Boston with 118 hits and an OBP of .360 this season.
• Ceddanne Rafaela has been key for Boston with 133 hits, an OBP of .292 plus a slugging percentage of .412.

Tigers Player Leaders

• Gleyber Torres has racked up a team-best .361 on-base percentage. He's batting .258 and slugging .390.
• Including all the qualifying players in MLB, his batting average is 74th, his on-base percentage is 19th, and he is 117th in slugging.
• Torres enters this game on a three-game hitting streak. In his last five games he is hitting .227 with a double, a walk and an RBI.
• Riley Greene has collected 155 hits while slugging .497. Both pace his team. He has a batting average of .260 with an on-base percentage of .315.
• Including all qualifying players, he is 68th in batting average, 104th in on-base percentage and 18th in slugging percentage.
• Spencer Torkelson is hitting .242 with 27 doubles, a triple, 31 home runs and 72 walks.
• Zach McKinstry is hitting .261 with 23 doubles, 11 triples, 12 home runs and 46 walks.

Red Sox vs Tigers Head to Head

• 9/26/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/14/2025: 6-5 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 5/13/2025: 10-9 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/12/2025: 14-2 DET (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/1/2024: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/31/2024: 2-1 DET (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/30/2024: 7-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/2/2024: 8-4 DET (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/1/2024: 6-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/31/2024: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

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