Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 1:12 p.m.

MLB action on Sunday includes the Boston Red Sox facing the Baltimore Orioles.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Red Sox vs Orioles Game Info

• Boston Red Sox (78-65) vs. Baltimore Orioles (69-74)
• Date: Sunday, September 6, 2026
• Time: 1:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-134) | BAL: (+114)
• Spread: BOS: -1.5 (+130) | BAL: +1.5 (-156)
• Total: 7 -- Over: (-115) | Under: (-105)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Payton Tolle (Red Sox) - 8-6, 3.23 ERA vs Kyle Bradish (Orioles) - 7-12, 4.01 ERA

This contest's pitching matchup is set, as the Red Sox will send Payton Tolle (8-6) to the mound, while Kyle Bradish (7-12) will take the ball for the Orioles. Tolle's team is 9-14-0 against the spread this season in his starts. When Tolle starts a game and his team is the favorite on the moneyline, they have a record of 11-5. The Orioles are 12-15-0 against the spread when Bradish starts. The Orioles have been the underdog on the moneyline in 12 of Bradish's starts this season, and they went 7-5 in those games.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (57.3%)

Red Sox vs Orioles Moneyline

• Boston is the favorite, -134 on the moneyline, while Baltimore is a +114 underdog despite being at home.

Red Sox vs Orioles Spread

• The Red Sox are 1.5-run road favorites on the runline against the Orioles. The Red Sox are +130 to cover, and the Orioles are -156.

Red Sox vs Orioles Over/Under

• An over/under of 7 has been set for Red Sox-Orioles on Sept. 6, with the over being -115 and the under -105.

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Red Sox vs Orioles Betting Trends

• The Red Sox have been victorious in 54, or 54.5%, of the 99 contests they have been chosen as favorites in this season.
• This year Boston has won 28 of 54 games when listed as at least -134 on the moneyline.
• The Red Sox's games have gone over the total in 66 of their 141 opportunities.
• In 141 games with a line this season, the Red Sox have a mark of 67-74-0 against the spread.
• The Orioles are 32-38 in games they were the underdog on the moneyline (winning 45.7% of those games).
• Baltimore has a 12-20 record (winning just 37.5% of its games) when it has played as a moneyline underdog of +114 or longer.
• In the 142 games bookmakers have set an over/under for the Orioles, they have combined with opponents to go over the total 71 times (71-67-4).
• The Orioles have collected a 73-69-0 record ATS this season (covering 51.4% of the time).

Red Sox Player Leaders

• Wilyer Abreu is hitting .256 with 34 doubles, four triples, 23 home runs and 64 walks. He has an on-base percentage of .335 while slugging .464.
• He is 68th in batting average, 61st in on-base percentage, and 36th in slugging among all qualified hitters in the majors.
• Ceddanne Rafaela has an OPS of .760, fueled by an OBP of .317 and a team-best slugging percentage of .443 this season. He's batting .282.
• His batting average ranks 19th among qualified players, his on-base percentage 92nd, and his slugging percentage 51st.
• Caleb Durbin has 112 hits this season and has a slash line of .248/.324/.381.
• Jarren Duran is batting .203 with a .259 OBP and 68 RBI for Boston this season.

Orioles Player Leaders

• Pete Alonso has 142 hits with a .357 on-base percentage and a .495 slugging percentage, all club-bests for the Orioles. He's batting .265.
• Including all the qualifying hitters in MLB, his batting average places him 53rd, his on-base percentage is 31st, and he is 17th in slugging.
• Gunnar Henderson has 25 doubles, five triples, 22 home runs and 60 walks while batting .222. He's slugging .401 with an on-base percentage of .306.
• He ranks 123rd in batting average, 113th in on-base percentage and 90th in slugging percentage in the big leagues.
• Leody Taveras is batting .217 with 15 doubles, six triples, eight home runs and 40 walks.
• Coby Mayo is batting .222 with 13 doubles, three triples, 19 home runs and 27 walks.

Red Sox vs Orioles Head to Head

• 9/5/2026: 5-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/4/2026: 1-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/3/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/22/2026: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/22/2026: 6-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/20/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/4/2026: 8-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2026: 8-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/2/2026: 4-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/26/2026: 5-3 BOS (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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