Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 1:12 a.m.

The Boston Red Sox will face the Baltimore Orioles in MLB action on Sunday.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Orioles Game Info

• Boston Red Sox (78-65) vs. Baltimore Orioles (69-74)
• Date: Sunday, September 6, 2026
• Time: 1:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-136) | BAL: (+116)
• Spread: BOS: -1.5 (+125) | BAL: +1.5 (-150)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Payton Tolle (Red Sox) - 8-6, 3.23 ERA vs Kyle Bradish (Orioles) - 7-12, 4.01 ERA

The Red Sox will give the nod to Payton Tolle (8-6, 3.23 ERA), who is eyeing win No. 9 on the season, and the Orioles will turn to Kyle Bradish (7-12, 4.01 ERA). Tolle and his team have a record of 9-14-0 against the spread when he starts. Tolle's team has a record of 11-5 this season when he starts and they are the favorite on the moneyline. The Orioles have a 12-15-0 record against the spread in Bradish's starts. The Orioles have been the moneyline underdog in 12 of Bradish's starts this season, and they went 7-5 in those matchups.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (57.8%)

Red Sox vs Orioles Moneyline

• Boston is a -136 favorite on the moneyline, while Baltimore is a +116 underdog at home.

Red Sox vs Orioles Spread

• The Red Sox are favored by 1.5 runs on the road versus the Orioles. The Red Sox are +125 to cover the spread, while the Orioles are -150.

Red Sox vs Orioles Over/Under

• The over/under for the Red Sox versus Orioles game on Sept. 6 has been set at 7.5, with -120 odds on the over and -102 odds on the under.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have been chosen as favorites in 99 games this year and have walked away with the win 54 times (54.5%) in those games.
• This season Boston has come away with a win 27 times in 50 chances when named as a favorite of at least -136 on the moneyline.
• The Red Sox and their opponents have hit the over in 66 of their 141 games with a total set by oddsmakers this season.
• In 141 games with a line this season, the Red Sox have a mark of 67-74-0 against the spread.
• The Orioles have compiled a 32-38 record in games they were listed as the moneyline underdog (winning 45.7% of those games).
• When playing as a moneyline underdog with odds of +116 or longer, Baltimore has a 10-18 record (winning only 35.7% of its games).
• The Orioles have combined with opponents to go over the total 71 times this season for a 71-67-4 record against the over/under.
• The Orioles are 73-69-0 against the spread this season.

Red Sox Player Leaders

• Wilyer Abreu has 34 doubles, four triples, 23 home runs and 64 walks while hitting .256. He has an on-base percentage of .335 and a slugging percentage of .464.
• Among qualifying batters in baseball, his batting average ranks 68th, his on-base percentage ranks 61st, and he is 36th in slugging.
• Ceddanne Rafaela leads Boston in slugging percentage (.443) thanks to 51 extra-base hits. He's batting .282 with an on-base percentage of .317.
• He is 19th in batting average, 92nd in on-base percentage and 51st in slugging among qualified hitters.
• Caleb Durbin has collected 112 base hits, an OBP of .324 and a slugging percentage of .381 this season.
• Jarren Duran has been key for Boston with 103 hits, an OBP of .259 plus a slugging percentage of .359.

Orioles Player Leaders

• Pete Alonso has a team-high OBP (.357) and slugging percentage (.495), while pacing the Orioles in hits (142, while batting .265).
• Including all qualified players, he ranks 53rd in batting average, while his on-base percentage ranks 31st and he is 17th in slugging.
• Gunnar Henderson is batting .222 with 25 doubles, five triples, 22 home runs and 60 walks. He's slugging .401 with an on-base percentage of .306.
• Including all qualifying hitters, his batting average puts him 123rd, his on-base percentage ranks 113th, and he is 90th in slugging.
• Leody Taveras is batting .217 with 15 doubles, six triples, eight home runs and 40 walks.
• Coby Mayo is hitting .222 with 13 doubles, three triples, 19 home runs and 27 walks.

Red Sox vs Orioles Head to Head

• 9/5/2026: 5-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/4/2026: 1-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/3/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/22/2026: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/22/2026: 6-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/20/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/4/2026: 8-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2026: 8-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/2/2026: 4-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/26/2026: 5-3 BOS (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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