Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for May 25

Odds updated as of 12:11 a.m.

The Boston Red Sox versus the Baltimore Orioles is on the MLB schedule for Sunday.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Orioles Game Info

• Boston Red Sox (27-27) vs. Baltimore Orioles (17-34)
• Date: Sunday, May 25, 2025
• Time: 1:35 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: MLB Network, NESN, and MASN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-130) | BAL: (+110)
• Spread: BOS: -1.5 (+146) | BAL: +1.5 (-178)
• Total: 9.5 -- Over: (-105) | Under: (-115)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Red Sox) - 4-1, 4.00 ERA vs Dean Kremer (Orioles) - 3-5, 5.50 ERA

The Red Sox will call on Walker Buehler (4-1) versus the Orioles and Dean Kremer (3-5). Buehler and his team are 5-2-0 ATS this season when he starts. Buehler has started four games with his team as the moneyline favorite and won each of them. The Orioles have a 3-7-0 record against the spread in Kremer's starts. The Orioles are 1-4 in Kremer's five starts this season that they were the underdog on the moneyline.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (51.3%)

Red Sox vs Orioles Moneyline

• Looking at the moneyline for Orioles-Red Sox, Baltimore is the underdog at +110, and Boston is -130 playing at home.

Red Sox vs Orioles Spread

• The Orioles are at +1.5 on the runline against the Red Sox. The Orioles are -178 to cover the spread, and the Red Sox are +146.

Red Sox vs Orioles Over/Under

• The over/under for the Red Sox versus Orioles contest on May 25 has been set at 9.5, with -105 odds on the over and -115 odds on the under.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have been chosen as favorites in 38 games this year and have walked away with the win 19 times (50%) in those games.
• This season Boston has been victorious eight times in 18 chances when named as a favorite of at least -130 on the moneyline.
• The Red Sox and their opponents have gone over in 26 of their 54 games with a total set by sportsbooks this season.
• In 54 games with a line this season, the Red Sox have a mark of 28-26-0 against the spread.
• The Orioles have won 36.4% of the games this season they were the underdog on the moneyline (8-14).
• Baltimore has a 1-7 record (winning only 12.5% of its games) when playing as a moneyline underdog of +110 or longer.
• The Orioles have combined with opponents to go over the total 26 times this season for a 26-23-2 record against the over/under.
• The Orioles have collected a 16-35-0 record against the spread this season.

Red Sox Player Leaders

• Rafael Devers leads Boston with an OBP of .412 this season while batting .297 with 40 walks and 35 runs scored. He has a slugging percentage of .550.
• He ranks 19th in batting average, fifth in on-base percentage, and 12th in slugging among all qualified hitters in MLB.
• Jarren Duran leads Boston in slugging percentage (.425) thanks to 22 extra-base hits. He's batting .268 with an on-base percentage of .319.
• His batting average ranks 65th among qualified players, his on-base percentage 99th, and his slugging percentage 77th.
• Wilyer Abreu is batting .262 with a .517 slugging percentage and 28 RBI this year.
• Abreu enters this matchup with two games in a row with at least one hit. During his last five outings he is hitting .235 with a double, a home run, a walk and an RBI.
• Ceddanne Rafaela has two home runs, 19 RBI and a batting average of .226 this season.

Orioles Player Leaders

• Cedric Mullins is hitting .225 with nine doubles, 10 home runs and 23 walks. He's slugging .451 with an on-base percentage of .322.
• Including all the qualified hitters in the big leagues, his batting average puts him 136th, his on-base percentage ranks 91st, and he is 59th in slugging.
• Ryan O'Hearn has collected 46 hits with a .405 OBP to pace his team in both. He has a batting average of .315 while slugging .500.
• Including all qualified players, he ranks 10th in batting average, sixth in on-base percentage and 28th in slugging percentage.
• Adley Rutschman has seven doubles, a triple, five home runs and 24 walks while hitting .214.
• Gunnar Henderson's .458 slugging percentage leads his team.

Red Sox vs Orioles Head to Head

• 5/24/2025: 2-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 5/24/2025: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/23/2025: 19-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/3/2025: 8-4 BOS (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/2/2025: 3-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 3/31/2025: 8-5 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/11/2024: 5-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/10/2024: 5-3 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/9/2024: 12-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/18/2024: 4-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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