Giants vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 25

Odds updated as of 1:11 a.m.

The San Francisco Giants are among the MLB squads in action on Sunday, versus the Washington Nationals.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Giants vs Nationals Game Info

• San Francisco Giants (30-22) vs. Washington Nationals (24-28)
• Date: Sunday, May 25, 2025
• Time: 1:35 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN2 and NBCS-BA

Giants vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-152) | WSH: (+128)
• Spread: SF: -1.5 (+110) | WSH: +1.5 (-132)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Giants vs Nationals Probable Starting Pitchers

Probable Pitchers: Robbie Ray (Giants) - 6-0, 2.67 ERA vs Mike Soroka (Nationals) - 1-2, 5.95 ERA

The Giants will give the ball to Robbie Ray (6-0, 2.67 ERA), who is eyeing win No. 7 on the season, and the Nationals will counter with Mike Soroka (1-2, 5.95 ERA). Ray's team is 8-2-0 against the spread this season in his starts. Ray's team has won 83.3% of his starts when they are favored on the moneyline (5-1). The Nationals have gone 1-3-0 against the spread when Soroka starts. The Nationals have been the moneyline underdog in four of Soroka's starts this season, and they went 1-3 in those matchups.

Giants vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (51.2%)

Giants vs Nationals Moneyline

• Washington is a +128 underdog on the moneyline, while San Francisco is a -152 favorite on the road.

Giants vs Nationals Spread

• The Nationals are hosting the Giants, and are +1.5 on the runline. The Nationals are +110 to cover the spread, and the Giants are -132.

Giants vs Nationals Over/Under

• A total of 8.5 runs has been set for the Giants-Nationals game on May 25, with the over available at -105 and the under at -115.

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Giants vs Nationals Betting Trends

• The Giants have been favorites in 33 games this season and have come away with the win 20 times (60.6%) in those contests.
• This season San Francisco has come away with a win seven times in 12 chances when named as a favorite of at least -152 on the moneyline.
• The Giants and their opponents have gone over in 27 of their 52 games with a total set by sportsbooks this season.
• In 52 games with a line this season, the Giants have a mark of 25-27-0 against the spread.
• The Nationals have won 21 of the 39 games they were the underdog on the moneyline this season (53.8%).
• Washington has gone 11-12 when playing as a moneyline underdog with odds of +128 or longer (47.8%).
• The Nationals have had an over/under set by oddsmakers 50 times, and have combined with opponents to go over the total in 24 of those games (24-25-1).
• The Nationals have collected a 27-23-0 record against the spread this season.

Giants Player Leaders

• Jung Hoo Lee leads San Francisco in slugging percentage (.462) thanks to 22 extra-base hits. He has a .281 batting average and an on-base percentage of .329.
• Among all qualifying hitters in the majors, his batting average ranks 38th, his on-base percentage ranks 78th, and he is 54th in slugging.
• Lee has hit safely in five straight games. During his last five outings he is hitting .333 with two doubles, three walks and two RBIs.
• Wilmer Flores has two doubles, 10 home runs and 17 walks. He's batting .253 and slugging .429 with an on-base percentage of .320.
• He ranks 83rd in batting average, 95th in on-base percentage and 74th in slugging in MLB.
• Heliot Ramos leads San Francisco with 56 hits and a team-best slugging percentage of .482.
• Matt Chapman has been key for San Francisco with 39 hits, an OBP of .335 plus a slugging percentage of .401.

Nationals Player Leaders

• James Wood has accumulated a team-best OBP (.380) and slugging percentage (.543), while leading the Nationals in hits (56, while batting .284).
• He is 32nd in batting average, 21st in on-base percentage and 13th in slugging percentage among all qualifying hitters in the majors.
• C.J. Abrams is batting .295 with nine doubles, two triples, eight home runs and 11 walks. He's slugging .532 with an on-base percentage of .355.
• He is currently 22nd in batting average, 46th in on-base percentage and 17th in slugging percentage among all qualified hitters.
• Luis Garcia is batting .233 with nine doubles, four home runs and 11 walks.
• Nathaniel Lowe is batting .223 with eight doubles, eight home runs and 19 walks.

Giants vs Nationals Head to Head

• 5/24/2025: 3-0 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/23/2025: 4-0 SF (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/8/2024: 9-5 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/7/2024: 7-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/6/2024: 11-5 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/5/2024: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/10/2024: 7-1 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/9/2024: 5-3 WSH (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/8/2024: 8-1 WSH (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/23/2023: 6-1 WSH (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)

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