Red Sox vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 10

Odds updated as of 6:13 a.m.

The Boston Red Sox are among the MLB squads busy on Friday, up against the St. Louis Cardinals.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Cardinals Game Info

• Boston Red Sox (4-8) vs. St. Louis Cardinals (7-5)
• Date: Friday, April 10, 2026
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and NESN

Red Sox vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-142) | STL: (+120)
• Spread: BOS: -1.5 (+122) | STL: +1.5 (-146)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Red Sox vs Cardinals Probable Starting Pitchers

Probable Pitchers: Connelly Early (Red Sox) - 0-0, 2.89 ERA vs Dustin May (Cardinals) - 0-2, 15.95 ERA

The probable pitchers are Connelly Early for the Red Sox and Dustin May (0-2) for the Cardinals. Early has a record of 0-2-0 ATS in two starts with a spread this season. Early's team is 0-2 this season when he starts and they're favored on the moneyline. May has started two games with set spreads, and the Cardinals failed to cover in both chances. The Cardinals were named the moneyline underdog for two May starts this season -- they lost both.

Red Sox vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (54.4%)

Red Sox vs Cardinals Moneyline

• St. Louis is a +120 underdog on the moneyline, while Boston is a -142 favorite on the road.

Red Sox vs Cardinals Spread

• The Cardinals are +1.5 on the spread (-146 to cover), and Boston is +122 to cover the runline.

Red Sox vs Cardinals Over/Under

• An over/under of 7.5 has been set for Red Sox-Cardinals on April 10, with the over being -110 and the under -110.

Bet on Boston Red Sox vs. St. Louis Cardinals on FanDuel today!

Red Sox vs Cardinals Betting Trends

• The Red Sox have been chosen as favorites in 10 games this year and have walked away with the win four times (40%) in those games.
• Boston has a record of 3-3 when favored by -142 or more this year.
• The Red Sox and their opponents have hit the over in six of their 12 games with a total set by oddsmakers this season.
• In 12 games with a line this season, the Red Sox have a mark of 3-9-0 against the spread.
• The Cardinals have won six of the 10 games they were the moneyline underdog this season (60%).
• St. Louis is 2-3 (winning 40% of its games) when it has played as a moneyline underdog of +120 or longer.
• In the 12 games oddsmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total six times (6-5-1).
• The Cardinals have collected a 6-6-0 record against the spread this season (covering 50% of the time).

Red Sox Player Leaders

• Wilyer Abreu leads Boston in slugging percentage (.702) and total hits (18) this season. He's batting .383 with an on-base percentage of .408.
• Among all qualified batters in MLB, he is fourth in batting average, 20th in on-base percentage, and second in slugging.
• Willson Contreras leads Boston in OBP (.434) this season, fueled by 10 hits. He's batting .250 while slugging .425.
• He is 74th in batting average, 12th in on-base percentage and 70th in slugging in the majors.
• Contreras enters this game looking to extend his three-game hit streak. During his last five outings he is hitting .353 with a double, a home run, five walks and three RBIs.
• Ceddanne Rafaela is batting .324 with a .412 slugging percentage and four RBI this year.
• Rafaela enters this game with five games in a row with at least one hit. During his last five outings he is batting .467 with two walks and two RBIs.
• Masataka Yoshida has no home runs, but three RBI and a batting average of .250 this season.
• Yoshida enters this game on a two-game hitting streak. During his last five outings he is hitting .308 with two doubles, five walks and three RBIs.

Cardinals Player Leaders

• Jordan Walker has racked up 13 hits with a .682 slugging percentage, both team-high figures for the Cardinals. He's batting .295 and with an on-base percentage of .367.
• Including all the qualified players in MLB, his batting average puts him 34th, his on-base percentage is 47th, and he is fifth in slugging.
• Walker takes a five-game hitting streak into this game. In his last five games he is hitting .381 with four home runs, two walks and nine RBIs.
• Alec Burleson's .400 OBP paces his team. He has a batting average of .273 while slugging .386.
• His batting average is 52nd among all qualified players, his on-base percentage ranks 23rd, and he is 84th in slugging.
• JJ Wetherholt has a double, a home run and eight walks while batting .244.
• Ivan Herrera is hitting .195 with three doubles and 12 walks.

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