Mariners vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for April 10

Odds updated as of 5:12 a.m.

The MLB slate on Friday includes the Seattle Mariners facing the Houston Astros.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Mariners vs Astros Game Info

• Seattle Mariners (4-9) vs. Houston Astros (6-7)
• Date: Friday, April 10, 2026
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Mariners.TV and SCHN

Mariners vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-136) | HOU: (+116)
• Spread: SEA: -1.5 (+158) | HOU: +1.5 (-192)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Mariners vs Astros Probable Starting Pitchers

Probable Pitchers: Emerson Hancock (Mariners) - 1-1, 0.71 ERA vs Tatsuya Imai (Astros) - 1-0, 4.32 ERA

The Mariners will give the ball to Emerson Hancock (1-1, 0.71 ERA), who is eyeing win No. 2 on the season, and the Astros will counter with Tatsuya Imai (1-0, 4.32 ERA). Hancock has a record of 1-1-0 ATS in two starts with a spread this season. Hancock's team is 1-1 this season when he starts and they're favored on the moneyline. Imai has started two games with set spreads, and the Astros covered in both chances. The Astros have not been a moneyline underdog when Imai starts this season.

Mariners vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (53.8%)

Mariners vs Astros Moneyline

• Houston is the underdog, +116 on the moneyline, while Seattle is a -136 favorite at home.

Mariners vs Astros Spread

• The Mariners are hosting the Astros and are favored by 1.5 runs on the spread. The Mariners are +158 to cover the runline, with the Astros being -192.

Mariners vs Astros Over/Under

• A total of 7.5 runs has been set for the Mariners-Astros contest on April 10, with the over available at -110 and the under at -110.

Bet on Seattle Mariners vs. Houston Astros on FanDuel today!

Mariners vs Astros Betting Trends

• The Mariners have come away with three wins in the 10 contests they have been listed as the favorites in this season.
• This season Seattle has been victorious three times in seven chances when named as a favorite of at least -136 on the moneyline.
• The Mariners' games have gone over the total in five of their 13 opportunities.
• The Mariners are 4-9-0 against the spread in their 13 games with a line set by sportsbooks this season.
• The Astros have been listed as the moneyline underdog just two other times so far this season, and they won both games.
• Houston has played as a moneyline underdog of +116 or longer in only one game this season, which it won.
• The Astros have combined with opponents to go over the total nine times this season for a 9-4-0 record against the over/under.
• The Astros have covered 46.2% of their games this season, going 6-7-0 ATS.

Mariners Player Leaders

• Brendan Donovan leads Seattle with 12 hits and an OBP of .422, plus a team-best slugging percentage of .605. He's batting .316.
• Among qualifying hitters, he is 29th in batting average, his on-base percentage ranks 15th, and he is 14th in slugging.
• Randy Arozarena is hitting .250 with three doubles and eight walks, while slugging .318 with an on-base percentage of .389.
• He is 74th in batting average, 34th in on-base percentage and 124th in slugging in MLB.
• Cole Young has an OPS of .784, fueled by an OBP of .306 and a team-best slugging percentage of .478 this season.
• Young heads into this game with two games in a row with at least one hit. In his last five games he is batting .176 with a home run, a walk and three RBIs.
• Dominic Canzone is batting .200 with a .259 OBP and three RBI for Seattle this season.

Astros Player Leaders

• Yordan Alvarez has put up an on-base percentage of .500 and has 13 hits, both team-best figures for the Astros. He's batting .317 and slugging .683.
• Including all the qualifying hitters in the big leagues, his batting average ranks 27th, his on-base percentage is first, and he is fourth in slugging.
• Christian Walker leads his team with a .640 slugging percentage. He has a batting average of .340 with an on-base percentage of .400.
• Including all qualified hitters, he is 11th in batting average, 23rd in on-base percentage and 10th in slugging percentage.
• Jose Altuve is batting .333 with four doubles, two home runs and 12 walks.
• Carlos Correa is hitting .262 with two doubles, a home run and six walks.

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