Red Sox vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 1

Odds updated as of 2:12 a.m.

The Boston Red Sox will face the Houston Astros in MLB action on Friday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Red Sox vs Astros Game Info

• Boston Red Sox (12-19) vs. Houston Astros (12-20)
• Date: Friday, May 1, 2026
• Time: 7:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: NESN and SCHN

Red Sox vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-110) | HOU: (-106)
• Spread: BOS: +1.5 (-178) | HOU: -1.5 (+146)
• Total: 9.5 -- Over: (-105) | Under: (-115)

Red Sox vs Astros Probable Starting Pitchers

Probable Pitchers: Jake Bennett (Red Sox) - 0-0, 0.00 ERA vs Mike Burrows (Astros) - 1-3, 6.25 ERA

The Red Sox will give the nod to Jake Bennett and the Astros will turn to Mike Burrows (1-3, 6.25 ERA). Bennett did not pitch as the moneyline favorite in any games last season. When Burrows starts, the Astros are 1-5-0 against the spread. The Astros have been the moneyline underdog in three of Burrows' starts this season, and they went 1-2 in those games.

Red Sox vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (53.4%)

Red Sox vs Astros Moneyline

• The moneyline numbers for Red Sox vs. Astros reveal Boston as the favorite (-110) and Houston as the underdog (-106) on the road.

Red Sox vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the Red Sox. The Astros are +146 to cover, while the Red Sox are -178 to cover as a 1.5-run underdog on the runline.

Red Sox vs Astros Over/Under

• A combined run total of 9.5 has been set for Red Sox-Astros on May 1, with the over at -105 and the under at -115.

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Red Sox vs Astros Betting Trends

• The Red Sox have won in nine, or 45%, of the 20 contests they have been named as odds-on favorites in this year.
• This season Boston has come away with a win nine times in 20 chances when named as a favorite of at least -110 on the moneyline.
• The Red Sox's games have gone over the total in 16 of their 31 opportunities.
• The Red Sox are 10-21-0 against the spread in their 31 games that had a posted line this season.
• The Astros have been the underdog on the moneyline 15 total times this season. They've gone 6-9 in those games.
• Houston is 6-9 (winning 40% of its games) when it has played as a moneyline underdog of -106 or longer.
• The Astros have played in 32 games with an over/under set, and have combined with their opponents to go over the total 23 times (23-9-0).
• The Astros have collected a 12-20-0 record against the spread this season.

Red Sox Player Leaders

• Wilyer Abreu leads Boston with a slugging percentage of .482, fueled by 11 extra-base hits. He has a .307 batting average and an on-base percentage of .373.
• Among all qualified hitters, he is 19th in batting average, his on-base percentage ranks 32nd, and he is 41st in slugging.
• Willson Contreras leads Boston with 28 hits and an OBP of .375 this season. He's batting .262 and slugging .486.
• Among qualifying batters, he ranks 63rd in batting average, 29th in on-base percentage and 38th in slugging percentage.
• Contreras has picked up at least one hit in five games in a row. During his last five outings he is batting .368 with a double, three home runs, two walks and eight RBIs.
• Caleb Durbin has 17 hits this season and has a slash line of .172/.261/.263.
• Ceddanne Rafaela has been key for Boston with 25 hits, an OBP of .333 plus a slugging percentage of .379.

Astros Player Leaders

• Yordan Alvarez has accumulated a team-best OBP (.462) and slugging percentage (.737), while pacing the Astros in hits (42, while batting .356).
• Including all qualifying players, he ranks second in batting average, while his on-base percentage is first and he is first in slugging.
• Christian Walker has nine doubles, seven home runs and 13 walks while batting .293. He's slugging .552 with an on-base percentage of .366.
• He is 30th in batting average, 39th in on-base percentage and 17th in slugging percentage in the majors.
• Carlos Correa is batting .274 with seven doubles, two home runs and 15 walks.
• Jose Altuve has seven doubles, three home runs and 17 walks while batting .250.

Red Sox vs Astros Head to Head

• 4/1/2026: 6-4 HOU (Favorite: Red Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 3/31/2026: 9-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 3/30/2026: 8-1 HOU (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/13/2025: 4-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/12/2025: 14-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/11/2025: 7-6 HOU (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/3/2025: 6-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/2/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/1/2025: 2-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/21/2024: 4-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)

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