Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 10:15 a.m.

On Wednesday in MLB, the Tampa Bay Rays are up against the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Rays vs White Sox Game Info

• Tampa Bay Rays (72-72) vs. Chicago White Sox (55-90)
• Date: Wednesday, September 10, 2025
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and FDSSUN

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-136) | CHW: (+116)
• Spread: TB: -1.5 (+122) | CHW: +1.5 (-146)
• Total: 8.5 -- Over: (+102) | Under: (-124)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Griffin Jax (Rays) - 1-7, 4.81 ERA vs TBA (White Sox)

The Rays will look to Griffin Jax (1-7), while the White Sox's starting pitcher has not yet been announced. Jax and his team failed to cover the spread in his only opportunity this season as a starter. Jax's team lost his only start as a favorite this season.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (69.1%)

Rays vs White Sox Moneyline

• Looking at the moneyline for White Sox-Rays, Chicago is the underdog at +116, and Tampa Bay is -136 playing on the road.

Rays vs White Sox Spread

• The Rays are 1.5-run road favorites on the runline against the White Sox. The Rays are +122 to cover, and the White Sox are -146.

Rays vs White Sox Over/Under

• Rays versus White Sox, on Sept. 10, has an over/under of 8.5, with the over being +102 and the under -124.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have been victorious in 39, or 58.2%, of the 67 contests they have been chosen as favorites in this season.
• Tampa Bay has a record of 21-18 when favored by -136 or more this year.
• The Rays and their opponents have gone over the total this season in 60 of their 139 opportunities.
• The Rays have an against the spread record of 61-78-0 in 139 games with a line this season.
• The White Sox have won 51 of the 137 games they were the underdog on the moneyline this season (37.2%).
• When playing as a moneyline underdog with odds of +116 or longer, Chicago has a 41-70 record (winning just 36.9% of its games).
• The White Sox have played in 140 games with an over/under set, and have combined with opponents to go over the total 66 times (66-66-8).
• The White Sox have an 80-60-0 record ATS this season (covering 57.1% of the time).

Rays Player Leaders

• Junior Caminero has 142 hits, which is tops among Tampa Bay hitters this season, while batting .261 with 67 extra-base hits. He has an on-base percentage of .301 and a slugging percentage of .535.
• He ranks 70th in batting average, 123rd in on-base percentage, and 11th in slugging among qualifying hitters in baseball.
• Caminero has hit safely in two games in a row. During his last five outings he is hitting .200 with a double, a home run and an RBI.
• Yandy Diaz is slashing .290/.348/.468 this season and leads the Rays with an OPS of .816.
• Among qualifiers, he ranks 13th in batting average, 40th in on-base percentage and 42nd in slugging percentage.
• Brandon Lowe has collected 119 base hits, an OBP of .314 and a slugging percentage of .485 this season.
• Chandler Simpson has been key for Tampa Bay with 101 hits, an OBP of .320 plus a slugging percentage of .335.
• Simpson brings a two-game hitting streak into this matchup. During his last five outings he is hitting .250 with an RBI.

White Sox Player Leaders

• Andrew Benintendi is batting .248 with 16 doubles, two triples, 18 home runs and 37 walks. He's slugging .433 with an on-base percentage of .312.
• Benintendi heads into this game on a four-game hitting streak. In his last five games he is hitting .294 with a double, a home run, three walks and five RBIs.
• Lenyn Sosa has 123 hits while slugging .435. Both pace his team. He has a batting average of .265 with an on-base percentage of .297.
• Including all qualifying players, he is 54th in batting average, 128th in on-base percentage and 76th in slugging percentage.
• Chase Meidroth is batting .265 with 15 doubles, four home runs and 41 walks.
• Mike Tauchman has 15 doubles, a triple, eight home runs and 41 walks while batting .270.

Rays vs White Sox Head to Head

• 9/9/2025: 5-4 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/23/2025: 11-9 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/27/2024: 8-7 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/26/2024: 9-4 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/30/2023: 12-9 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

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