Rays vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for ALCS Game 4 on Oct. 17

Odds updated as of 11:12 a.m.

In MLB action on Saturday, the Tampa Bay Rays play the Cleveland Guardians for Game 4 of the ALCS.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Rays vs Guardians Game Info

• Tampa Bay Rays (98-64) vs. Cleveland Guardians (85-77)
• Date: Saturday, October 17, 2026
• Time: 8:08 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: TBS, truTV, and HBO Max

Rays vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-116) | CLE: (-102)
• Spread: TB: -1.5 (+155) | CLE: +1.5 (-188)
• Total: 6.5 -- Over: (-110) | Under: (-110)

Rays vs Guardians Probable Starting Pitchers

Probable Pitchers: Nick Martínez (Rays) - 15-6, 3.10 ERA vs Shawn Armstrong (Guardians) - 2-1, 4.58 ERA

The Rays will give the nod to Nick Martinez (15-6, 3.10 ERA) against the Guardians and Shawn Armstrong (2-1, 4.58 ERA). Martinez and his team have a record of 20-12-0 against the spread when he starts. Martinez's team has a record of 11-4 this season when he starts and they are the favorite on the moneyline. Last season when Armstrong pitched his team finished 1-1-0 against the spread. Armstrong and his team were underdogs on the moneyline each game he pitched a season ago.

Rays vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (53%)

Rays vs Guardians Moneyline

• The Rays vs Guardians moneyline has Tampa Bay as a -116 favorite, while Cleveland is a -102 underdog at home.

Rays vs Guardians Spread

• The Guardians are hosting the Rays, and are +1.5 on the runline. The Guardians are +155 to cover the spread, and the Rays are -188.

Rays vs Guardians Over/Under

• An over/under of 6.5 has been set for Rays-Guardians on Oct. 17, with the over being -110 and the under -110.

Bet on Tampa Bay Rays vs. Cleveland Guardians on FanDuel today!

Rays vs Guardians Betting Trends

• The Rays have come away with 68 wins in the 107 contests they have been listed as the favorites in this season.
• This year Tampa Bay has won 66 of 100 games when listed as at least -116 on the moneyline.
• The Rays and their opponents have gone over the total this season in 77 of their 165 opportunities.
• The Rays are 88-77-0 against the spread in their 165 games that had a posted line this season.
• The Guardians have put together a 32-30 record in games they were the underdog on the moneyline (winning 51.6% of those games).
• When it has played as a moneyline underdog with odds of -102 or longer, Cleveland has a 30-27 record (winning 52.6% of its games).
• The Guardians have combined with opponents to hit the over on the total 78 times this season for a 78-82-0 record against the over/under.
• The Guardians have gone 77-83-0 against the spread this season.

Rays Player Leaders

• Junior Caminero leads Tampa Bay in total hits (170) this season while batting .276 with 68 extra-base hits. He has an on-base percentage of .360 and a slugging percentage of .524.
• Among qualified batters in MLB, he ranks 33rd in batting average, 30th in on-base percentage, and sixth in slugging.
• Yandy Diaz has an OPS of .805, fueled by an OBP of .359 and a team-best slugging percentage of .446 this season. He's batting .293.
• Among qualifying batters, he ranks 10th in batting average, 33rd in on-base percentage and 50th in slugging percentage.
• Liam Hicks leads Tampa Bay in OBP (.367) this season, fueled by 136 hits.
• Chandler Simpson has been key for Tampa Bay with 175 hits, an OBP of .333 plus a slugging percentage of .356.
• Simpson takes a two-game hitting streak into this game. In his last five games he is batting .200 with a triple and three RBIs.

Guardians Player Leaders

• Chase DeLauter is leading the Guardians with 142 hits. He's batting .287 and slugging .457 with an on-base percentage of .363.
• Including all the qualified hitters in the majors, he is 16th in batting average, 24th in on-base percentage and 43rd in slugging percentage.
• Steven Kwan has a .382 OBP while slugging .349. Both are team-highs. He has a batting average of .282.
• He is 21st in batting average, seventh in on-base percentage and 131st in slugging percentage in the majors.
• Jose Ramirez is hitting .235 with 27 doubles, 12 home runs and 60 walks.
• Brayan Rocchio is hitting .253 with 25 doubles, two triples, 15 home runs and 38 walks.

Rays vs Guardians Head to Head

• 10/15/2026: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +112)
• 10/13/2026: 3-1 TB (Favorite: Rays, Spread: -1.5, Total: 6.5, Favorite Moneyline: -128, Underdog Moneyline: +114)
• 10/12/2026: 7-3 CLE (Favorite: Rays, Spread: -1.5, Total: 6.5, Favorite Moneyline: -166, Underdog Moneyline: +148)
• 7/26/2026: 1-0 TB (Favorite: Rays, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/25/2026: 3-0 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/24/2026: 11-3 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/28/2026: 1-0 TB (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/27/2026: 3-2 TB (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/7/2025: 2-1 CLE (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/6/2025: 3-2 CLE (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)

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