Pirates vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 8

Odds updated as of 6:11 p.m.

Tuesday's slate in the MLB includes a matchup between the Pittsburgh Pirates and the St. Louis Cardinals.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Pirates vs Cardinals Game Info

• Pittsburgh Pirates (4-7) vs. St. Louis Cardinals (4-6)
• Date: Tuesday, April 8, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and FDSMW

Pirates vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-138) | STL: (+118)
• Spread: PIT: -1.5 (+152) | STL: +1.5 (-184)
• Total: 6.5 -- Over: (-105) | Under: (-115)

Pirates vs Cardinals Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 1-0, 1.46 ERA vs Sonny Gray (Cardinals) - 1-0, 5.73 ERA

The Pirates will give the ball to Paul Skenes (1-0, 1.46 ERA), who is eyeing win No. 2 on the season, and the Cardinals will turn to Sonny Gray (1-0, 5.73 ERA). Skenes has a record of 1-1-0 ATS in two starts with a spread this season. Skenes' team is 1-1 this season when he starts and they're favored on the moneyline. Gray has started two games with set spreads, and the Cardinals covered in both chances. The Cardinals were named the moneyline underdog for one Gray start this season -- they won.

Pirates vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (52.4%)

Pirates vs Cardinals Moneyline

• The Pirates vs Cardinals moneyline has Pittsburgh as a -138 favorite, while St. Louis is a +118 underdog on the road.

Pirates vs Cardinals Spread

• The Pirates are favored by 1.5 runs at home against the Cardinals. The Pirates are +152 to cover the spread, while the Cardinals are -184.

Pirates vs Cardinals Over/Under

• A total of 6.5 runs has been set for the Pirates-Cardinals contest on April 8, with the over available at -105 and the under at -115.

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Pirates vs Cardinals Betting Trends

• The Pirates have come away with two wins in the four contests they have been listed as the favorites in this season.
• Pittsburgh has been listed as a favorite of -138 or more on two occasions this season and split those games.
• The Pirates and their opponents have hit the over in six of their 11 games with a total set by oddsmakers this season.
• The Pirates have posted a record of 3-8-0 against the spread this season.
• The Cardinals have been the underdog on the moneyline six total times this season. They've gone 3-3 in those games.
• St. Louis has yet to play a game with moneyline odds of +118 or longer.
• The Cardinals have had an over/under set by bookmakers 10 times, and have combined with opponents to go over the total in eight of those games (8-1-1).
• The Cardinals have put together a 4-6-0 record against the spread this season (covering 40% of the time).

Pirates Player Leaders

• Oneil Cruz has a double, two home runs and nine walks while batting .222. He has an on-base percentage of .362 and a slugging percentage of .417.
• Among qualifying batters in the majors, he is 115th in batting average, 58th in on-base percentage, and 88th in slugging.
• Isiah Kiner-Falefa has a slash line of .343/.439/.371 this season and a team-best OPS of .810.
• His batting average ranks 16th among qualified players, his on-base percentage 12th, and his slugging percentage 111th.
• Kiner-Falefa takes a two-game streak with at least one hit into this one. In his last five games he is hitting .353 with a double, a walk and three RBI.
• Ke'Bryan Hayes leads Pittsburgh with 10 hits. He is batting .263 this season and three of his hits have gone for extra bases.
• Hayes has logged a hit or more in six straight games. During his last 10 games he is batting .263 with a double, a triple, a home run, four walks and five RBI.
• Andrew McCutchen is batting .348 with a .423 OBP and four RBI for Pittsburgh this season.

Cardinals Player Leaders

• Brendan Donovan has a team-best slugging percentage (.575) and leads the Cardinals in hits (15). He's batting .375 and with an on-base percentage of .409.
• Including all the qualified players in the big leagues, his batting average ranks ninth, his on-base percentage is 27th, and he is 31st in slugging.
• Donovan hopes to build on a four-game hitting streak in this matchup. In his last five games he is batting .500 with two doubles, a home run, a walk and six RBI.
• Lars Nootbaar is batting .302 with a double, two home runs and seven walks. He's slugging .465 with an on-base percentage of .412.
• He is currently 40th in batting average, 24th in on-base percentage and 62nd in slugging percentage among all qualifying hitters.
• Nolan Arenado has accumulated an on-base percentage of .439, a team-high for the Cardinals.
• Victor Scott II is batting .281 with a double, a home run and five walks.

Pirates vs Cardinals Head to Head

• 4/7/2025: 8-4 PIT (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/19/2024: 3-2 PIT (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/18/2024: 10-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/17/2024: 3-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/16/2024: 4-0 STL (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/24/2024: 5-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/23/2024: 2-1 STL (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 7/22/2024: 2-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/4/2024: 3-2 STL (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/3/2024: 5-4 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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