Phillies vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 16

Odds updated as of 7:11 a.m.

Friday's slate in the MLB includes a matchup between the Philadelphia Phillies and the Pittsburgh Pirates.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Pirates Game Info

• Philadelphia Phillies (25-18) vs. Pittsburgh Pirates (15-29)
• Date: Friday, May 16, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and SportsNet PT

Phillies vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-220) | PIT: (+184)
• Spread: PHI: -1.5 (-106) | PIT: +1.5 (-113)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Phillies vs Pirates Probable Starting Pitchers

Probable Pitchers: Ranger Suarez (Phillies) - 1-0, 5.91 ERA vs Andrew Heaney (Pirates) - 2-3, 3.15 ERA

This contest's pitching matchup is set, as the Phillies will send Ranger Suarez (1-0) to the mound, while Andrew Heaney (2-3) will get the nod for the Pirates. Suarez has a record of 1-1-0 ATS in two starts with a spread this season. Suarez's team is 1-1 this season when he starts and they're favored on the moneyline. The Pirates have gone 3-5-0 against the spread when Heaney starts. The Pirates are 2-4 in Heaney's six starts this season that they were the underdog on the moneyline.

Phillies vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (65.7%)

Phillies vs Pirates Moneyline

• Looking at the moneyline for Pirates-Phillies, Pittsburgh is the underdog at +184, and Philadelphia is -220 playing at home.

Phillies vs Pirates Spread

• The Pirates are at the Phillies, and are +1.5 on the runline. The Pirates are -106 to cover the spread, and the Phillies are -113.

Phillies vs Pirates Over/Under

• Phillies versus Pirates, on May 16, has an over/under of 8.5, with the over being -110 and the under -110.

Bet on Philadelphia Phillies vs. Pittsburgh Pirates on FanDuel today!

Phillies vs Pirates Betting Trends

• The Phillies have been chosen as favorites in 35 games this year and have walked away with the win 21 times (60%) in those games.
• Philadelphia has a record of 4-1 when favored by -220 or more this year.
• The Phillies and their opponents have gone over in 19 of their 42 games with a total set by sportsbooks this season.
• The Phillies are 21-21-0 against the spread in their 42 games with a line set by sportsbooks this season.
• The Pirates have gone 10-19 in games they were the underdog on the moneyline (winning 34.5% of those games).
• Pittsburgh has a 2-3 record (winning 40% of its games) when it has played as a moneyline underdog of +184 or longer.
• The Pirates have had an over/under set by oddsmakers 43 times, and have combined with opponents to go over the total in 17 of those games (17-24-2).
• The Pirates have collected an 18-25-0 record ATS this season.

Phillies Player Leaders

• Kyle Schwarber has 41 hits and an OBP of .393, both of which are best among Philadelphia hitters this season. He has a .261 batting average and a slugging percentage of .580.
• He ranks 70th in batting average, 15th in on-base percentage, and eighth in slugging among all qualifying batters in baseball.
• Bryce Harper is batting .236 with nine doubles, seven home runs and 31 walks. He's slugging .422 with an on-base percentage of .358.
• He ranks 110th in batting average, 48th in on-base percentage and 76th in slugging in MLB.
• Trea Turner leads Philadelphia in slugging percentage (.377) powered by nine extra-base hits.
• Bryson Stott has three home runs, 21 RBI and a batting average of .258 this season.
• Stott brings a two-game hitting streak into this matchup. During his last five outings he is batting .167 with two walks and an RBI.

Pirates Player Leaders

• Oneil Cruz has 31 hits, a team-best for the Pirates. He's batting .238 and slugging .462 with an on-base percentage of .369.
• Including all qualifying hitters in the big leagues, he is 108th in batting average, 36th in on-base percentage and 51st in slugging percentage.
• Andrew McCutchen is hitting .254 with seven doubles, three home runs and 18 walks. He's slugging .385 with an on-base percentage of .352.
• He ranks 85th in batting average, 54th in on-base percentage and 104th in slugging percentage in the big leagues.
• Ke'Bryan Hayes has accumulated a team-high .325 slugging percentage.
• Isiah Kiner-Falefa has three doubles, a triple, a home run and seven walks while hitting .283.

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