Phillies vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 2:12 a.m.

In MLB action on Wednesday, the Philadelphia Phillies play the Miami Marlins.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Marlins Game Info

• Philadelphia Phillies (92-65) vs. Miami Marlins (77-80)
• Date: Wednesday, September 24, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and FDSFL

Phillies vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-198) | MIA: (+166)
• Spread: PHI: -1.5 (+105) | MIA: +1.5 (-126)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Phillies vs Marlins Probable Starting Pitchers

Probable Pitchers: Jesús Luzardo (Phillies) - 14-7, 4.08 ERA vs Ryan Weathers (Marlins) - 2-1, 3.21 ERA

The Phillies will call on Jesus Luzardo (14-7) versus the Marlins and Ryan Weathers (2-1). Luzardo and his team are 14-16-0 ATS this season when he starts. Luzardo's team is 15-9 this season when he starts and they are the moneyline favorite. The Marlins are 4-2-0 ATS in Weathers' six starts with a set spread. The Marlins have a 2-3 record in Weathers' five starts this season when they were the moneyline underdog.

Phillies vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (67.9%)

Phillies vs Marlins Moneyline

• The moneyline numbers for Phillies vs. Marlins reveal Philadelphia as the favorite (-198) and Miami as the underdog (+166) on the road.

Phillies vs Marlins Spread

• The Marlins are at +1.5 on the runline against the Phillies. The Marlins are -126 to cover the spread, and the Phillies are +105.

Phillies vs Marlins Over/Under

• Phillies versus Marlins on Sept. 24 has an over/under of 8.5 runs, with the odds on the over -102 and the under set at -120.

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Phillies vs Marlins Betting Trends

• The Phillies have been favorites in 117 games this season and have come away with the win 75 times (64.1%) in those contests.
• Philadelphia has a record of 22-4 when favored by -198 or more this year.
• The Phillies' games have gone over the total in 64 of their 150 opportunities.
• The Phillies have an against the spread mark of 77-73-0 in 150 games with a line this season.
• The Marlins have been the moneyline underdog 123 total times this season. They've gone 60-63 in those games.
• Miami has a record of 11-16 when it has played as a moneyline underdog with odds of +166 or longer (40.7%).
• The Marlins have combined with opponents to hit the over on the total 76 times this season for a 76-75-1 record against the over/under.
• The Marlins have an 88-64-0 record against the spread this season (covering 57.9% of the time).

Phillies Player Leaders

• Kyle Schwarber has 141 hits and an OBP of .367, both of which are tops among Philadelphia hitters this season. He has a .241 batting average and a slugging percentage of .562.
• Among all qualifying hitters in baseball, he ranks 108th in batting average, 12th in on-base percentage, and fourth in slugging.
• Bryce Harper has 32 doubles, 27 home runs and 68 walks. He's batting .263 and slugging .495 with an on-base percentage of .358.
• Among all qualified, he ranks 53rd in batting average, 23rd in on-base percentage and 18th in slugging percentage.
• Bryson Stott has 123 hits this season and has a slash line of .255/.328/.387.
• Nick Castellanos has 17 home runs, 71 RBI and a batting average of .256 this season.
• Castellanos takes a four-game hitting streak into this matchup. During his last five outings he is hitting .357 with a home run, a walk and five RBIs.

Marlins Player Leaders

• Otto Lopez is batting .250 with 20 doubles, 15 home runs and 44 walks. He's slugging .373 with an on-base percentage of .310.
• Including all qualifying hitters, he ranks 91st in batting average, while his on-base percentage is 107th and he is 128th in slugging.
• Lopez enters this game on a five-game hitting streak. During his last five outings he is batting .333 with two doubles, a home run and three RBIs.
• Agustin Ramirez has collected 121 hits to pace his team. He has a batting average of .233 while slugging .422 with an on-base percentage of .291.
• His batting average ranks 125th among all qualified players, his on-base percentage is 130th, and he is 78th in slugging.
• Xavier Edwards has racked up a team-high OBP (.337) and slugging percentage (.352).
• Eric Wagaman is hitting .248 with 27 doubles, three triples, nine home runs and 32 walks.

Phillies vs Marlins Head to Head

• 9/23/2025: 6-5 MIA (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 9/7/2025: 5-4 MIA (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/6/2025: 4-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/5/2025: 9-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 6/19/2025: 2-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/18/2025: 4-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 6/16/2025: 5-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/20/2025: 7-5 MIA (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 4/19/2025: 11-10 PHI (Favorite: Phillies, Spread: -1.5, Total: 10.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 4/18/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -220, Underdog Moneyline: +184)

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