Phillies vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 8

Odds updated as of 2:12 a.m.

The Philadelphia Phillies will take on the Houston Astros in MLB action on Tuesday.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Astros Game Info

• Philadelphia Phillies (81-63) vs. Houston Astros (73-71)
• Date: Tuesday, September 8, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: TBS, NBCS-PH, and SCHN

Phillies vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-142) | HOU: (+120)
• Spread: PHI: -1.5 (+136) | HOU: +1.5 (-164)
• Total: 9 -- Over: (-104) | Under: (-118)

Phillies vs Astros Probable Starting Pitchers

Probable Pitchers: Andrew Painter (Phillies) - 3-8, 5.55 ERA vs Hayden Wesneski (Astros) - 4-1, 3.18 ERA

The Phillies will call on Andrew Painter (3-8) against the Astros and Hayden Wesneski (4-1). Painter and his team are 4-15-0 ATS this season when he starts. Painter's team has a record of 7-5 this season when he starts and they are the favorite on the moneyline. The Astros are 6-1-0 against the spread when Wesneski starts. The Astros were named the moneyline underdog for one Wesneski start this season -- they won.

Phillies vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (54.4%)

Phillies vs Astros Moneyline

• Houston is a +120 underdog on the moneyline, while Philadelphia is a -142 favorite at home.

Phillies vs Astros Spread

• The Astros are +1.5 on the spread (-164 to cover), and Philadelphia is +136 to cover the runline.

Phillies vs Astros Over/Under

• Phillies versus Astros, on Sept. 8, has an over/under of 9, with the over being -104 and the under -118.

Bet on Philadelphia Phillies vs. Houston Astros on FanDuel today!

Phillies vs Astros Betting Trends

• The Phillies have won in 70, or 65.4%, of the 107 contests they have been named as odds-on favorites in this year.
• This season Philadelphia has been victorious 55 times in 72 chances when named as a favorite of at least -142 on the moneyline.
• The Phillies and their opponents have gone over the total this season in 65 of their 140 opportunities.
• The Phillies are 59-81-0 against the spread in their 140 games that had a posted line this season.
• The Astros have put together a 38-36 record in games they were the underdog on the moneyline (winning 51.4% of those games).
• Houston has an 11-14 record (winning 44% of its games) when playing as a moneyline underdog of +120 or longer.
• The Astros have had an over/under set by bookmakers 144 times, and have combined with opponents to go over the total in 72 of those games (72-65-7).
• The Astros are 72-72-0 against the spread this season.

Phillies Player Leaders

• Bryce Harper leads Philadelphia in OBP (.389) this season, fueled by 137 hits. He has a .271 batting average and a slugging percentage of .499.
• Among all qualified hitters in the majors, his batting average ranks 40th, his on-base percentage ranks fourth, and he is 13th in slugging.
• Luis Arraez has hit six homers this season while driving in 57 runs. He's batting .316 this season and slugging .429 with an on-base percentage of .347.
• Among qualified hitters, his batting average ranks him first, his on-base percentage 45th, and his slugging percentage 61st.
• Kyle Schwarber leads Philadelphia in total hits (125) this season, and 61 of those have gone for extra bases.
• Schwarber takes a three-game hitting streak into this game. In his last five games he is hitting .278 with three home runs, three walks and four RBIs.
• Bryson Stott has 10 home runs, 61 RBI and a batting average of .252 this season.

Astros Player Leaders

• Yordan Alvarez has a team-high OBP (.432) and slugging percentage (.599), and leads the Astros in hits (160, while batting .314).
• Including all qualified hitters, he is second in batting average, while his on-base percentage is first and he is first in slugging.
• Isaac Paredes is hitting .258 with 25 doubles, a triple, 18 home runs and 61 walks. He's slugging .421 with an on-base percentage of .357.
• His batting average is 66th among all qualified players, his on-base percentage ranks 34th, and he is 71st in slugging.
• Christian Walker is hitting .227 with 25 doubles, a triple, 24 home runs and 45 walks.
• Jose Altuve is hitting .247 with 20 doubles, two triples, 15 home runs and 39 walks.

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