Phillies vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for June 26

Odds updated as of 2:12 a.m.

In MLB action on Thursday, the Philadelphia Phillies play the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this game.

Phillies vs Astros Game Info

• Philadelphia Phillies (47-33) vs. Houston Astros (47-33)
• Date: Thursday, June 26, 2025
• Time: 2:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-PH

Phillies vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-156) | HOU: (+132)
• Spread: PHI: -1.5 (+112) | HOU: +1.5 (-134)
• Total: 7.5 -- Over: (-104) | Under: (-118)

Phillies vs Astros Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 6-2, 2.77 ERA vs Hunter Brown (Astros) - 8-3, 1.88 ERA

This contest's pitching matchup is set, as the Phillies will send Cristopher Sanchez (6-2) to the mound, while Hunter Brown (8-3) will answer the bell for the Astros. Sanchez's team is 9-6-0 against the spread in his starts this season. When Sanchez starts a game and his team is the favorite on the moneyline, they have a record of 11-2. The Astros have gone 10-5-0 against the spread when Brown starts. The Astros are 2-1 in Brown's three starts this season that they were the underdog on the moneyline.

Phillies vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (57.4%)

Phillies vs Astros Moneyline

• Looking at the moneyline for Astros-Phillies, Houston is the underdog at +132, and Philadelphia is -156 playing on the road.

Phillies vs Astros Spread

• The Astros are +1.5 on the run line against the Phillies. The Astros are -134 to cover, and the Phillies are +112.

Phillies vs Astros Over/Under

• An over/under of 7.5 has been set for Phillies-Astros on June 26, with the over being -104 and the under -118.

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Phillies vs Astros Betting Trends

• The Phillies have been chosen as favorites in 62 games this year and have walked away with the win 41 times (66.1%) in those games.
• Philadelphia has a record of 27-8 in contests when sportsbooks favor them by -156 or more on the moneyline.
• The Phillies' games have gone over the total in 31 of their 76 opportunities.
• The Phillies are 38-38-0 against the spread in their 76 games that had a posted line this season.
• The Astros are 14-10 in games they were the underdog on the moneyline (winning 58.3% of those games).
• Houston has gone 2-1 when playing as a moneyline underdog with odds of +132 or longer (66.7%).
• The Astros have played in 79 games with a set over/under, and have combined with their opponents to go over the total 31 times (31-46-2).
• The Astros have a 41-38-0 record against the spread this season (covering 51.9% of the time).

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia with 73 hits and an OBP of .380 this season. He has a .250 batting average and a slugging percentage of .534.
• Among qualified hitters in baseball, he is 101st in batting average, 15th in on-base percentage, and 13th in slugging.
• Trea Turner has hit nine homers this season while driving in 35 runs. He's batting .299 this season and slugging .445 with an on-base percentage of .354.
• His batting average ranks 16th among qualified players, his on-base percentage 41st, and his slugging percentage 62nd.
• Turner brings a three-game streak with at least one hit into this contest. In his last five games he is batting .286 with a double and an RBI.
• Nick Castellanos has collected 85 base hits, an OBP of .322 and a slugging percentage of .437 this season.
• Alec Bohm is batting .283 with a .323 OBP and 36 RBI for Philadelphia this season.

Astros Player Leaders

• Jeremy Pena has a team-best OBP (.380) and slugging percentage (.495), and paces the Astros in hits (101, while batting .325).
• Including all qualified hitters in the majors, his batting average puts him fifth, his on-base percentage is 15th, and he is 24th in slugging.
• Pena enters this game on a three-game hitting streak. In his last five games he is batting .368 with three doubles, two home runs, two walks and three RBIs.
• Isaac Paredes is batting .254 with 10 doubles, a triple, 16 home runs and 42 walks. He's slugging .468 with an on-base percentage of .359.
• Including all qualifying hitters, his batting average puts him 87th, his on-base percentage ranks 36th, and he is 43rd in slugging.
• Jose Altuve is batting .264 with 10 doubles, 12 home runs and 26 walks.
• Jake Meyers is hitting .307 with 13 doubles, a triple, three home runs and 23 walks.

Phillies vs Astros Head to Head

• 6/25/2025: 2-0 HOU (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 1-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/28/2024: 10-0 HOU (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2024: 5-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/26/2024: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/30/2023: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/29/2023: 6-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/28/2023: 3-1 PHI (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 11/5/2022: 4-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 11/3/2022: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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