Panthers vs Sabres NHL Prediction, Odds, Picks, Best Bets for Oct. 12

On Monday in the NHL, the Florida Panthers are up against the Buffalo Sabres.

Get the latest NHL odds ahead of this game on FanDuel Sportsbook.

Panthers vs Sabres Game Info

• Florida Panthers (2-1-2) vs. Buffalo Sabres (2-3)
• Date: Monday, October 12, 2026
• Time: 1 p.m. ET
• Venue: KeyBank Center -- Buffalo, New York
• Coverage: ESPN+

Panthers vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Panthers vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (67.4%)

Panthers vs Sabres Puck Line

• The Sabres are underdogs by 1.5 goals (-245 to cover). And Florida, the favorite, is +194.

Panthers vs Sabres Over/Under

• The over/under for the Panthers versus Sabres game on Oct. 12 has been set at 6.5, with +110 odds on the over and -134 odds on the under.

Panthers vs Sabres Moneyline

• Florida is a -118 favorite on the moneyline, while Buffalo is a -102 underdog at home.

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