Panthers vs Red Wings NHL Prediction, Odds, Picks, Best Bets for Oct. 15

The Florida Panthers versus the Detroit Red Wings is on the NHL schedule for Wednesday.

Get the latest NHL odds ahead of this matchup on FanDuel Sportsbook.

Panthers vs Red Wings Game Info

• Florida Panthers (3-1) vs. Detroit Red Wings (2-1)
• Date: Wednesday, October 15, 2025
• Time: 7 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: TNT

Panthers vs Red Wings Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Panthers vs Red Wings Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Panthers win (56.6%)

Panthers vs Red Wings Puck Line

• The Panthers are 1.5-goal favorites against the Red Wings. The Panthers are +168 to cover the spread, and the Red Wings are -210.

Panthers vs Red Wings Over/Under

• An over/under of 5.5 has been set for Panthers-Red Wings on Oct. 15, with the over being -128 and the under +104.

Panthers vs Red Wings Moneyline

• Florida is the favorite, -144 on the moneyline, while Detroit is a +120 underdog despite being at home.

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