Padres vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for May 17

Odds updated as of 8:13 a.m.

The San Diego Padres are among the MLB squads busy on Saturday, up against the Seattle Mariners.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Mariners Game Info

• San Diego Padres (27-16) vs. Seattle Mariners (24-19)
• Date: Saturday, May 17, 2025
• Time: 8:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and ROOT Sports NW

Padres vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-184) | SEA: (+154)
• Spread: SD: -1.5 (+112) | SEA: +1.5 (-134)
• Total: 8 -- Over: (-118) | Under: (-104)

Padres vs Mariners Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 5-2, 3.05 ERA vs Emerson Hancock (Mariners) - 1-2, 6.91 ERA

The Padres will call on Nick Pivetta (5-2) against the Mariners and Emerson Hancock (1-2). Pivetta and his team have a record of 6-2-0 against the spread when he starts. Pivetta's team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. The Mariners are 4-2-0 against the spread when Hancock starts. The Mariners are 3-1 in Hancock's four starts this season that they were the moneyline underdog.

Padres vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (61.8%)

Padres vs Mariners Moneyline

• The Padres vs Mariners moneyline has San Diego as a -184 favorite, while Seattle is a +154 underdog on the road.

Padres vs Mariners Spread

• The Mariners are +1.5 on the run line against the Padres. The Mariners are -134 to cover, and the Padres are +112.

Padres vs Mariners Over/Under

• The Padres-Mariners game on May 17 has been given an over/under of 8 runs. The over is set at -118 and the under at -104.

Bet on San Diego Padres vs. Seattle Mariners on FanDuel today!

Padres vs Mariners Betting Trends

• The Padres have been favorites in 23 games this season and have come away with the win 16 times (69.6%) in those contests.
• This season San Diego has come away with a win six times in eight chances when named as a favorite of at least -184 on the moneyline.
• Contests with the Padres have gone over the total set by oddsmakers in 19 of 42 chances this season.
• The Padres have posted a record of 25-17-0 against the spread this season.
• The Mariners have compiled a 9-8 record in games they were listed as the moneyline underdog (winning 52.9% of those games).
• Seattle has yet to play as a moneyline underdog of +154 or longer.
• The Mariners have played in 43 games with a set over/under, and have combined with their opponents to go over the total 25 times (25-16-2).
• The Mariners have gone 21-22-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 50 hits, batting .307 this season with 17 extra-base hits. He has an on-base percentage of .380 and a slugging percentage of .552.
• Among qualified hitters in the majors, he ranks 14th in batting average, 25th in on-base percentage, and 11th in slugging.
• Manny Machado leads the Padres with an OPS of .879. He has a slash line of .331/.401/.478 this season.
• He ranks fifth in batting average, eighth in on-base percentage and 36th in slugging among qualified hitters.
• Luis Arraez has collected 45 base hits, an OBP of .333 and a slugging percentage of .417 this season.
• Arraez has recorded a hit in four games in a row. During his last five outings he is batting .300 with a double.
• Xander Bogaerts has three home runs, 20 RBI and a batting average of .238 this season.

Mariners Player Leaders

• Cal Raleigh has 39 hits, a team-best for the Mariners. He's batting .250 and slugging .571 with an on-base percentage of .371.
• Including all qualifying hitters, he is 88th in batting average, while his on-base percentage ranks 33rd and he is seventh in slugging.
• Raleigh hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .313 with a double, two home runs, three walks and five RBIs.
• Jorge Polanco has six doubles, 10 home runs and eight walks while hitting .324. He's slugging .649 with an on-base percentage of .372.
• Julio Rodriguez has accumulated a slugging percentage of .408, a team-best for the Mariners.
• J.P. Crawford leads his team with a .385 on-base percentage.

Padres vs Mariners Head to Head

• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/7/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/6/2023: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/14/2022: 6-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)

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