Padres vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 2:13 a.m.

The MLB's Sunday schedule includes the San Diego Padres facing the San Francisco Giants.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Padres vs Giants Game Info

• San Diego Padres (80-68) vs. San Francisco Giants (62-87)
• Date: Sunday, September 13, 2026
• Time: 7:20 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCSN and Peacock

Padres vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-130) | SF: (+110)
• Spread: SD: -1.5 (+136) | SF: +1.5 (-164)
• Total: 6.5 -- Over: (-130) | Under: (+106)

Padres vs Giants Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 2-2, 3.43 ERA vs Logan Webb (Giants) - 8-8, 4.10 ERA

This contest's pitching matchup is set, as the Padres will send Nick Pivetta (2-2) to the mound, while Logan Webb (8-8) will get the nod for the Giants. Pivetta and his team have a record of 2-3-0 against the spread when he starts. Pivetta and his team have won each of the three games he's started as the moneyline favorite. The Giants have a 12-14-0 ATS record in Webb's 26 starts that had a set spread. The Giants have been the underdog on the moneyline in 10 of Webb's starts this season, and they went 2-8 in those games.

Padres vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (56.9%)

Padres vs Giants Moneyline

• San Diego is the favorite, -130 on the moneyline, while San Francisco is a +110 underdog despite being at home.

Padres vs Giants Spread

• The Giants are at +1.5 on the runline against the Padres. The Giants are -164 to cover the spread, and the Padres are +136.

Padres vs Giants Over/Under

• A combined run total of 6.5 has been set for Padres-Giants on Sept. 13, with the over at -130 and the under at +106.

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Padres vs Giants Betting Trends

• The Padres have come away with 41 wins in the 70 contests they have been listed as the favorites in this season.
• This year San Diego has won 27 of 45 games when listed as at least -130 on the moneyline.
• The Padres and their opponents have gone over the total this season in 66 of their 148 opportunities.
• The Padres are 85-63-0 against the spread in their 148 games that had a posted line this season.
• The Giants have won 37 of the 100 games they were the underdog on the moneyline this season (37%).
• In games it has played as a moneyline underdog with odds of +110 or longer, San Francisco has a record of 26-37 (41.3%).
• The Giants have played in 146 games with a set over/under, and have combined with their opponents to go over the total 71 times (71-65-10).
• The Giants have gone 70-76-0 against the spread this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in OBP (.356), slugging percentage (.457) and total hits (164) this season. He has a .286 batting average.
• Among all qualifying batters in the majors, his batting average ranks 15th, his on-base percentage ranks 35th, and he is 42nd in slugging.
• Tatis hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .474 with a triple, a home run, five walks and two RBIs.
• Jackson Merrill is hitting .248 with 24 doubles, four triples, 25 home runs and 39 walks. He's slugging .439 with an on-base percentage of .299.
• Among all qualified, he ranks 78th in batting average, 119th in on-base percentage and 56th in slugging percentage.
• Merrill heads into this game looking to extend his three-game hit streak. During his last five outings he is batting .524 with two doubles, a triple, three home runs, a walk and 10 RBIs.
• Manny Machado is batting .221 with a .407 slugging percentage and 80 RBI this year.
• Xander Bogaerts has been key for San Diego with 108 hits, an OBP of .323 plus a slugging percentage of .326.
• Bogaerts heads into this game on a three-game hitting streak. During his last five outings he is hitting .368 with two doubles, three walks and two RBIs.

Giants Player Leaders

• Rafael Devers has totaled 144 hits with a .340 on-base percentage and a .525 slugging percentage, all club-bests for the Giants. He's batting .258.
• Including all qualified players in the majors, he ranks 66th in batting average, 54th in on-base percentage and fifth in slugging percentage.
• Jung Hoo Lee has 29 doubles, four triples, nine home runs and 27 walks while hitting .279. He's slugging .404 with an on-base percentage of .321.
• He is currently 25th in batting average, 83rd in on-base percentage and 87th in slugging percentage among all qualified hitters.
• Bryce Eldridge is batting .267 with 22 doubles, 16 home runs and 55 walks.
• Drew Gilbert is hitting .235 with 14 doubles, three triples, nine home runs and 34 walks.

Padres vs Giants Head to Head

• 9/12/2026: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 9/11/2026: 7-5 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/2/2026: 5-4 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: +110)
• 8/1/2026: 6-5 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +134)
• 7/31/2026: 7-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +132)
• 7/30/2026: 4-1 SF (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/6/2026: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: -106)
• 5/5/2026: 10-5 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/4/2026: 3-2 SF (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -194, Underdog Moneyline: +150)
• 4/1/2026: 7-1 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)

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