Padres vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 4

Odds updated as of 5:19 a.m.

On Monday in MLB, the San Diego Padres are up against the Arizona Diamondbacks.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Diamondbacks Game Info

• San Diego Padres (62-50) vs. Arizona Diamondbacks (53-59)
• Date: Monday, August 4, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and SDPA

Padres vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-136) | ARI: (+116)
• Spread: SD: -1.5 (+116) | ARI: +1.5 (-140)
• Total: 9.5 -- Over: (-100) | Under: (-122)

Padres vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: JP Sears (Padres) - 7-9, 4.95 ERA vs Brandon Pfaadt (Diamondbacks) - 10-7, 5.03 ERA

The Padres will give the ball to JP Sears (7-9, 4.95 ERA), who is eyeing win No. 8 on the season, and the Diamondbacks will counter with Brandon Pfaadt (10-7, 5.03 ERA). Sears and his team are 12-10-0 ATS this season when he starts. Sears' team has won 75% of his starts when they are favored on the moneyline (3-1). The Diamondbacks have a 12-10-0 ATS record in Pfaadt's 22 starts that had a set spread. The Diamondbacks have been the moneyline underdog in 10 of Pfaadt's starts this season, and they went 5-5 in those games.

Padres vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (53.4%)

Padres vs Diamondbacks Moneyline

• San Diego is the favorite, -136 on the moneyline, while Arizona is a +116 underdog despite being at home.

Padres vs Diamondbacks Spread

• The Padres are favored by 1.5 runs on the road against the Diamondbacks. The Padres are +116 to cover the spread, while the Diamondbacks are -140.

Padres vs Diamondbacks Over/Under

• Padres versus Diamondbacks, on Aug. 4, has an over/under of 9.5, with the over being -100 and the under -122.

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Padres vs Diamondbacks Betting Trends

• The Padres have been favorites in 56 games this season and have come away with the win 34 times (60.7%) in those contests.
• San Diego has a record of 24-14 when favored by -136 or more this year.
• The Padres' games have gone over the total in 46 of their 110 opportunities.
• In 110 games with a line this season, the Padres have a mark of 61-49-0 against the spread.
• The Diamondbacks have been the underdog on the moneyline 41 total times this season. They've finished 18-23 in those games.
• Arizona has a 10-7 record (winning 58.8% of its games) when it has played as a moneyline underdog of +116 or longer.
• The Diamondbacks have played in 108 games with an over/under set, and have combined with their opponents to go over the total 54 times (54-48-6).
• The Diamondbacks have collected a 49-59-0 record against the spread this season (covering 45.4% of the time).

Padres Player Leaders

• Manny Machado has 129 hits to go with a slugging percentage of .501, both of which rank first among San Diego hitters this season. He has a .299 batting average and an on-base percentage of .359.
• Among all qualifying hitters in MLB, he ranks ninth in batting average, 30th in on-base percentage, and 20th in slugging.
• Fernando Tatis Jr. is batting .264 with 19 doubles, two triples, 17 home runs and 63 walks. He's slugging .442 with an on-base percentage of .367.
• His batting average is 68th among qualified players, his on-base percentage 23rd, and his slugging percentage 69th.
• Luis Arraez is batting .298 with a .407 slugging percentage and 41 RBI this year.
• Arraez has recorded at least one base hit in 16 straight games. In his last 10 outings he is hitting .415 with three doubles, a home run, three walks and four RBIs.
• Xander Bogaerts has been key for San Diego with 107 hits, an OBP of .339 plus a slugging percentage of .383.
• Bogaerts enters this game on a four-game hitting streak. In his last five games he is hitting .263 with a walk and an RBI.

Diamondbacks Player Leaders

• Geraldo Perdomo has racked up a team-high .426 slugging percentage. He's batting .278 with an on-base percentage of .378.
• Including all qualified players in the majors, he ranks 35th in batting average, 12th in on-base percentage and 82nd in slugging percentage.
• Corbin Carroll has 19 doubles, 14 triples, 22 home runs and 37 walks while hitting .247. He's slugging .543 with an on-base percentage of .323.
• Including all qualifying hitters, his batting average puts him 107th, his on-base percentage ranks 87th, and he is 10th in slugging.
• Ketel Marte has accumulated 85 hits with a .390 on-base percentage, leading the Diamondbacks in both categories.
• Lourdes Gurriel Jr. is batting .244 with 21 doubles, two triples, 12 home runs and 26 walks.

Padres vs Diamondbacks Head to Head

• 7/10/2025: 4-3 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/9/2025: 8-2 ARI (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/8/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/7/2025: 6-3 ARI (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/15/2025: 8-2 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/14/2025: 8-7 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/13/2025: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/29/2024: 11-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/28/2024: 5-0 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/27/2024: 5-3 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)

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