Orioles vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 24

Odds updated as of 4:16 a.m.
The MLB's Thursday slate includes the Washington Nationals taking on the Baltimore Orioles.
We've got you covered, in terms of the most important information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.
Nationals vs Orioles Game Info
- Washington Nationals (11-13) vs. Baltimore Orioles (9-14)
- Date: Thursday, April 24, 2025
- Time: 6:45 p.m. ET
- Venue: Nationals Park -- Washington, District of Columbia
- Coverage: MLB Network, MASN, and MASN2
Nationals vs Orioles Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: WSH: (-110) | BAL: (-106)
- Spread: WSH: +1.5 (-178) | BAL: -1.5 (+146)
- Total: 8.5 -- Over: (-122) | Under: (-100)
Nationals vs Orioles Probable Starting Pitchers
Probable Pitchers: MacKenzie Gore (Nationals) - 2-2, 3.41 ERA vs Cade Povich (Orioles) - 0-2, 6.38 ERA
The Nationals will look to MacKenzie Gore (2-2) against the Orioles and Cade Povich (0-2). Gore and his team have a record of 1-4-0 against the spread when he starts. When Gore starts a game and his team is the favorite on the moneyline, they have a record of 1-2. The Orioles have a 1-3-0 ATS record in Povich's four starts that had a set spread. The Orioles were the moneyline underdog for one Povich start this season -- they lost.
Nationals vs Orioles Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (51.7%)
Nationals vs Orioles Moneyline
- Baltimore is the underdog, -106 on the moneyline, while Washington is a -110 favorite at home.
Nationals vs Orioles Spread
- The Orioles are 1.5-run favorites against the spread for this matchup with the Nationals. The Orioles are +146 to cover, while the Nationals are -178 to cover as a 1.5-run underdog on the runline.
Nationals vs Orioles Over/Under
- The over/under for Nationals-Orioles on April 24 is 8.5. The over is -122, and the under is -100.
Bet on Washington Nationals vs. Baltimore Orioles on FanDuel today!
Nationals vs Orioles Betting Trends
- The Nationals have been favorites in five games this season and have come away with the win two times (40%) in those contests.
- Washington has a record of 2-3 when favored by -110 or more this year.
- The Nationals and their opponents have gone over in 12 of their 24 games with a total set by sportsbooks this season.
- In 24 games with a line this season, the Nationals have a mark of 12-12-0 against the spread.
- The Orioles have won four of the nine games they were the underdog on the moneyline this season (44.4%).
- Baltimore has a 4-5 record (winning 44.4% of its games) when it has played as a moneyline underdog of -106 or longer.
- The Orioles have played in 23 games with an over/under set, and have combined with their opponents to go over the total 14 times (14-7-2).
- The Orioles have an 8-15-0 record ATS this season.
Nationals Player Leaders
- James Wood leads Washington with 23 hits, batting .256 this season with 13 extra-base hits. He has an on-base percentage of .356 and a slugging percentage of .578.
- Among qualifying hitters in baseball, his batting average ranks 72nd, his on-base percentage ranks 49th, and he is 12th in slugging.
- Wood hopes to build on a two-game hitting streak in this matchup. During his last five outings he is hitting .350 with two doubles, two home runs, two walks and five RBI.
- Keibert Ruiz has a slash line of .325/.372/.450 this season and a team-best OPS of .822.
- Among qualifying hitters, his batting average ranks him 14th, his on-base percentage 37th, and his slugging percentage 56th.
- Ruiz takes a four-game streak with at least one hit into this contest. During his last five outings he is batting .300 with two doubles and two RBI.
- Nate Lowe is batting .291 with a .488 slugging percentage and 19 RBI this year.
- Lowe heads into this game with four games in a row with at least one hit. During his last five outings he is batting .316 with a home run, two walks and three RBI.
- Joshua Evan Bell has four home runs, 11 RBI and a batting average of .141 this season.
Orioles Player Leaders
- Cedric Mullins has racked up 22 hits with a .441 on-base percentage and a .608 slugging percentage, all club-bests for the Orioles. He's batting .297.
- Including all the qualified players in MLB, he ranks 30th in batting average, fourth in on-base percentage and eighth in slugging percentage.
- Mullins heads into this matchup on a five-game hitting streak. During his last five outings he is hitting .316 with two home runs, four walks and two RBI.
- Adley Rutschman is batting .214 with two doubles, four home runs and 12 walks. He's slugging .381 with an on-base percentage of .313.
- His batting average is 117th among all qualified players, his on-base percentage ranks 99th, and he is 96th in slugging.
- Ryan O'Hearn has three doubles, three home runs and six walks while hitting .281.
- Jordan Westburg is hitting .190 with two doubles, a triple, four home runs and five walks.
Nationals vs Orioles Head to Head
- 4/23/2025: 4-3 WSH (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
- 4/22/2025: 7-0 WSH (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
- 8/14/2024: 4-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
- 8/13/2024: 9-3 WSH (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
- 5/8/2024: 7-6 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
- 5/7/2024: 3-0 WSH (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
- 9/27/2023: 5-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -255, Underdog Moneyline: +210)
- 9/26/2023: 1-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
- 4/19/2023: 4-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
- 4/18/2023: 1-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!