Detroit Lions Vs. Buffalo Bills Odds, Betting Lines, Score & Stats (September 17, 2026)

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Odds not available yet.

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Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Popular Bets

8 Leg Parlay

+899

Jahmyr Gibbs 80+ Yards

Jahmyr Gibbs - Alt Rushing + Receiving Yds

James Cook 60+ Yards

James Cook - Alt Rushing Yds

Khalil Shakir 40+ Yards

Khalil Shakir - Alt Receiving Yds

D.J. Moore 30+ Yards

D.J. Moore - Alt Receiving Yds

Amon-Ra St. Brown 70+ Yards

Amon-Ra St. Brown - Alt Receiving Yds

Jameson Williams 30+ Yards

Jameson Williams - Alt Receiving Yds

Dalton Kincaid 3+ Receptions

Dalton Kincaid - Alt Receptions

Sam LaPorta 3+ Receptions

Sam LaPorta - Alt Receptions

18 People Placed

6 Leg Parlay

+34662

Josh Allen 300+ Yards

Josh Allen - Alt Passing Yds

Jared Goff 350+ Yards

Jared Goff - Alt Passing Yds

Josh Allen 40+ Yards

Josh Allen - Alt Rushing Yds

James Cook 80+ Yards

James Cook - Alt Rushing Yds

Amon-Ra St. Brown 100+ Yards

Amon-Ra St. Brown - Alt Receiving Yds

Sam LaPorta 70+ Yards

Sam LaPorta - Alt Receiving Yds

15 People Placed

Odds not available yet.

Check back closer to game time!

Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Player

QB • 100 Average Yards

Top Projected Fantasy Performers

Detroit Lions

17.6 Points

16.7 Points

14.3 Points

9.9 Points

Buffalo Bills

22.9 Points

15.6 Points

9.4 Points

8.8 Points

Injuries

Detroit Lions

NameStatus

LBDamone Clark

IRUndisclosed

DEPayton Turner

IRBack

RBIsiah Pacheco

IRBack

Buffalo Bills

NameStatus

RBTy Johnson

QHamstring

DLT.J. Sanders

QKnee

Team Stats

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DET

BUF

5.53

Offensive EPA

19.38

9.48

Passing EPA

29.64

9.48

Rushing EPA

7.9

Defensive EPA

7.98

5.53

Def Pass EPA

6.84

3.16

Def Rush EPA

13.68

Game Log

Detroit Lions

DateOpponentResultSpread

NOW 30 - 31-6.5

Buffalo Bills

DateOpponentResultSpread

HOUW 36 - 31-1.5

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