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Philadelphia Eagles Vs. Buffalo Bills Odds, Betting Lines, Score & Stats (December 28, 2025) | FanDuel Research

FanDuel Research>
NFL>
Matchups>
Philadelphia Eagles Vs. Buffalo Bills

Featured Player Props

View all NFL Player Props

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Top Projected Fantasy Performers

Injuries

Team Stats

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Game Log

More NFL Games

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This Christmas, Pass The Leg

Christmas Pass The Leg NFL Parlay/SGP 30% PBT

Bet $5, Get $250 if You Win!

Philadelphia Eagles

18.1 Points

RBSaquon Barkley

14.7 Points

11.4 Points

WRDeVonta Smith

10.6 Points

Buffalo Bills

18.3 Points

16.3 Points

WRKhalil Shakir

9.5 Points

TEDalton Kincaid

7.4 Points

PHI

BUF

6.493

Offensive EPA

12.6787

9.7395

Passing EPA

14.0133

5.1944

Rushing EPA

11.3441

0

Defensive EPA

4.6711

-5.1944

Def Pass EPA

-2.6692

3.8958

Def Rush EPA

13.346

Line Movement

These graphs show how the spread, moneyline, and total have shifted at FanDuel Sportsbook over time.

Spread

Eagles

Open: +3

Bills

Open: -3

Moneyline

Eagles

Open: +136

Bills

Open: -162

Total

Over

Open: 44.5

Under

Open: 44.5

FOX

Philadelphia Eagles

10-5 | 1st in NFC East | 3rd in NFC

SpreadMoneylineTotal

@

Buffalo Bills

11-4 | 2nd in AFC East | 6th in AFC

SpreadMoneylineTotal

FOX

Highmark Stadium

NFL

2 Best NFL Bets and Predictions for 49ers at Colts on Monday Night Football

2 Best NFL Bets and Predictions for 49ers at Colts on Monday Night Football

Jim Sannes

• 10h

Philip Rivers will play his second game since returning Monday as the Colts host the 49ers. Which bets stand out at FanDuel Sportsbook?

3 Best NFL Player Prop Bets for Monday Night Football: 49ers at Colts

Jim Sannes

• 10h

3 Best NFL Player Prop Bets for Monday Night Football: 49ers at Colts

10 Best Fantasy Football Waiver Wire Adds Heading Into NFL Week 17

Austan Kas

• 3h

10 Best Fantasy Football Waiver Wire Adds Heading Into NFL Week 17

Week 17 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

FanDuel Staff

• 9h

Week 17 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

Christian McCaffrey Fantasy Football Week 16: Stats and Projections vs. Colts

Data Skrive

• 7d

Christian McCaffrey Fantasy Football Week 16: Stats and Projections vs. Colts

Brock Purdy Fantasy Football Week 16: Stats and Projections vs. Colts

Data Skrive

• 7d

Brock Purdy Fantasy Football Week 16: Stats and Projections vs. Colts

Jauan Jennings Fantasy Football Week 16: Stats and Projections vs. Colts

Data Skrive

• 7d

Jauan Jennings Fantasy Football Week 16: Stats and Projections vs. Colts

2 Best NFL Bets and Player Props for Patriots at Ravens on Sunday Night Football

Austan Kas

• 1d

2 Best NFL Bets and Player Props for Patriots at Ravens on Sunday Night Football

4 Best NFL Player Prop Bets for Week 16

Jim Sannes

• 3d

4 Best NFL Player Prop Bets for Week 16

3 Best NFL Touchdown Prop Bets for Week 16

Jim Sannes

• 3d

3 Best NFL Touchdown Prop Bets for Week 16

Popular Bets

Odds not available yet.

Check back closer to game time!

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Josh Allen

QB • 234 Average YD

Jalen Hurts

QB • 209 Average YD

Philadelphia Eagles

NameStatus

-Ogbo Okoronkwo

IRTriceps

WRQuez Watkins

QUndisclosed

FBBen VanSumeren

IRKnee

OLBAzeez Ojulari

IRHamstring

LBNakobe Dean

QHamstring

WRJohnny Wilson

IRKnee

Buffalo Bills

NameStatus

KMatt Prater

QQuadriceps

DTJordan Phillips

QAnkle

DTDaQuan Jones

QUndisclosed

SAFJordan Poyer

QHamstring

OLBShaq Thompson

QNeck

WRCurtis Samuel

IRElbow

Philadelphia Eagles

DateOpponentResultSpread

@

WASW 29 - 18-7

vs

LVW 0 - 31-11.5

@

LACL 19 - 22-1.5

vs

CHIL 24 - 15-7

@

DALL 21 - 24-3

vs

DETW 9 - 16-1.5

Buffalo Bills

DateOpponentResultSpread

@

CLEW 23 - 20-10.5

@

NEW 35 - 31-2.5

vs

CINW 34 - 39-5.5

@

PITW 26 - 7-3

@

HOUL 19 - 23-4.5

vs

TBW 32 - 44-5.5