NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 7

There is a lot to be excited about on the Week 7 NFL schedule, including the New England Patriots squaring off against the Chicago Bears.
Here is what you need to know regarding the betting odds for Week 7 in the NFL.
Bears vs. Patriots
After securing a 31-23 victory versus the Falcons in their previous game, the Chicago Bears (4-2) will host the New England Patriots (4-2), who are coming off a 26-19 win over the Jets, at Soldier Field. The game is scheduled for 8:15 p.m. ET on Thursday, Oct. 22.
- Game Preview: New England Patriots at Chicago Bears
- Projected Favorite: Bears (58.54% win probability)
- Spread: Chicago (-3)
- Total: 50.5 -- Over: (-110) | Under: (-110)
- Time: 8:15 p.m. ET
- Channel: Amazon Prime Video
Bet on Chicago vs. New England with FanDuel Sportsbook.
Saints vs. Steelers
Against the New Orleans Saints (2-4), who have the 30th-ranked run defense this season, Jaylen Warren and the Pittsburgh Steelers (4-2) should have success running the ball when the two teams come together on Sunday, Oct. 25 at 9:30 a.m. ET. Warren has been one of the NFL's top runners this year, ranking seventh-best in the league in rushing yards.
- Game Preview: Pittsburgh Steelers vs. New Orleans Saints
- Projected Favorite: Steelers (70.43% win probability)
- Spread: Pittsburgh (-3)
- Total: 44.5 -- Over: (-112) | Under: (-108)
- Time: 9:30 a.m. ET
- Channel: NFL Network
Bet on New Orleans vs. Pittsburgh with FanDuel Sportsbook.
Titans vs. Browns
Two sputtering offenses will meet up on Oct. 25 at 1 p.m. ET, when the Cleveland Browns (4-2) and their 28th-ranked scoring unit visit the Tennessee Titans (1-5), who rank 31st in the NFL in scoring.
- Game Preview: Cleveland Browns at Tennessee Titans
- Projected Favorite: Browns (60.76% win probability)
- Spread: Cleveland (-1.5)
- Total: 37.5 -- Over: (-105) | Under: (-115)
- Time: 1 p.m. ET
- Channel: CBS
Bet on Tennessee vs. Cleveland with FanDuel Sportsbook.
Panthers vs. Buccaneers
The Carolina Panthers (3-2) will host the Tampa Bay Buccaneers (1-5) on Sunday at 1 p.m. ET.
- Game Preview: Tampa Bay Buccaneers at Carolina Panthers
- Projected Favorite: Panthers (69.35% win probability)
- Spread: Carolina (-3.5)
- Total: 44.5 -- Over: (-110) | Under: (-110)
- Time: 1 p.m. ET
- Channel: FOX
Bet on Carolina vs. Tampa Bay with FanDuel Sportsbook.
Vikings vs. Colts
The 1 p.m. ET game on Oct. 25 between the Indianapolis Colts (2-4) and the Minnesota Vikings (5-0) should be a fun matchup, as Jonathan Taylor has been one of the NFL's top runners this season, and the Vikings have been a top-five run defense, ranking fifth-best in the NFL with 86.6 rushing yards allowed per game.
- Game Preview: Indianapolis Colts at Minnesota Vikings
- Projected Favorite: Vikings (70.83% win probability)
- Spread: Minnesota (-6.5)
- Total: 41.5 -- Over: (-110) | Under: (-110)
- Time: 1 p.m. ET
- Channel: CBS
Bet on Minnesota vs. Indianapolis with FanDuel Sportsbook.
Texans vs. Giants
The 1 p.m. ET game on Oct. 25 between the Houston Texans (2-4) and the New York Giants (3-2-1) should be a fun matchup, as C.J. Stroud has been one of the league's top passers this year, and the Giants have a top-five pass defense, ranking fifth-best in the NFL at 190.2 passing yards allowed per contest.
- Game Preview: New York Giants at Houston Texans
- Projected Favorite: Texans (68.23% win probability)
- Spread: Houston (-9.5)
- Total: 43.5 -- Over: (-102) | Under: (-120)
- Time: 1 p.m. ET
- Channel: FOX
Bet on Houston vs. New York with FanDuel Sportsbook.
Falcons vs. 49ers
After a 23-17 win versus the Commanders in their last tilt, the San Francisco 49ers (6-0) will visit the Atlanta Falcons (2-4), who are coming off a 31-23 loss to the Bears. Kickoff is slated for 1 p.m. ET on Sunday, Oct. 25.
- Game Preview: San Francisco 49ers at Atlanta Falcons
- Projected Favorite: 49ers (52.83% win probability)
- Spread: San Francisco (-3.5)
- Total: 48.5 -- Over: (-120) | Under: (-102)
- Time: 1 p.m. ET
- Channel: FOX
Bet on Atlanta vs. San Francisco with FanDuel Sportsbook.
Ravens vs. Bengals
On Sunday, Oct. 25 at 1 p.m. ET, the Baltimore Ravens (4-2) will attempt to rebound from their recent 13-10 loss to the Browns when they take on the Cincinnati Bengals (3-2) at M&T Bank Stadium. The Bengals won their previous tilt 31-24 versus the Dolphins.
- Game Preview: Cincinnati Bengals at Baltimore Ravens
- Projected Favorite: Ravens (73.27% win probability)
- Spread: Baltimore (-2.5)
- Total: 50.5 -- Over: (-118) | Under: (-104)
- Time: 1 p.m. ET
- Channel: CBS
Bet on Baltimore vs. Cincinnati with FanDuel Sportsbook.
Jets vs. Dolphins
The New York Jets (2-4) and the Miami Dolphins (0-5), who both lost their last tilt, will square off at 1 p.m. ET on Sunday, Oct. 25. In their previous games, the Jets lost 26-19 to the Patriots, and the Dolphins were defeated by the Bengals 31-24.
- Game Preview: Miami Dolphins at New York Jets
- Projected Favorite: Jets (63.76% win probability)
- Spread: New York (-4.5)
- Total: 39.5 -- Over: (-106) | Under: (-114)
- Time: 1 p.m. ET
- Channel: CBS
Bet on New York vs. Miami with FanDuel Sportsbook.
Cardinals vs. Broncos
When the Denver Broncos (4-2) and the Arizona Cardinals (2-4) go head to head on Sunday, Oct. 25 at 4:05 p.m. ET, they will both be aiming to maintain momentum after winning their previous game. The Broncos won 17-14 versus the Seahawks, and the Cardinals are coming off an 18-16 victory over the Rams.
- Game Preview: Denver Broncos at Arizona Cardinals
- Projected Favorite: Broncos (62.87% win probability)
- Spread: Denver (-4.5)
- Total: 43.5 -- Over: (-110) | Under: (-110)
- Time: 4:05 p.m. ET
- Channel: CBS
Bet on Arizona vs. Denver with FanDuel Sportsbook.
Lions vs. Packers
The Detroit Lions (3-2) and their league-worst pass defense may have a hard time slowing down the Green Bay Packers (4-2) and Christian Watson, one of the NFL's top receivers, when the Packers visit the Lions at Ford Field on Oct. 25 at 4:25 p.m. ET.
- Game Preview: Green Bay Packers at Detroit Lions
- Projected Favorite: Lions (69.95% win probability)
- Spread: Detroit (-3)
- Total: 52.5 -- Over: (-120) | Under: (-102)
- Time: 4:25 p.m. ET
- Channel: FOX
Bet on Detroit vs. Green Bay with FanDuel Sportsbook.
Raiders vs. Rams
The 4:25 p.m. ET game on Oct. 25 between the Las Vegas Raiders (3-3) and the Los Angeles Rams (2-4) should be a competitive matchup, as Kirk Cousins has been one of the NFL's top passers this year, and the Rams have a top-five pass defense, ranking second-best in the NFL at 167.0 passing yards surrendered per game.
- Game Preview: Los Angeles Rams at Las Vegas Raiders
- Projected Favorite: Rams (63.55% win probability)
- Spread: Los Angeles (-4.5)
- Total: 48.5 -- Over: (-110) | Under: (-110)
- Time: 4:25 p.m. ET
- Channel: FOX
Bet on Las Vegas vs. Los Angeles with FanDuel Sportsbook.
Matchup favorites and win projections are provided by numberFire.
Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!



