NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 14

The Week 14 NFL schedule features several top-tier games, including the matchup between the Indianapolis Colts and the Jacksonville Jaguars.

To pick up an edge before Week 14 in the NFL, read our betting preview below.

Lions vs. Cowboys

The Dallas Cowboys (6-5-1) and their 30th-ranked pass defense could have a hard time slowing down the Detroit Lions (7-5) and Amon-Ra St. Brown, one of the NFL's top pass-catchers, when the Cowboys visit the Lions at Ford Field on Dec. 4 at 8:15 p.m. ET.

• Game Preview: Dallas Cowboys at Detroit Lions
• Projected Favorite: Lions (63.57% win probability)
• Spread: Detroit (-3)
• Total: 54.5 -- Over: (-110) | Under: (-110)
• Time: 8:15 p.m. ET
• Channel: Amazon Prime Video

Bet on Detroit vs. Dallas with FanDuel Sportsbook.

Vikings vs. Commanders

At 1 p.m. ET on Dec. 7, the Minnesota Vikings (4-8) and their bottom-five (28th in NFL) scoring offense will take on the Washington Commanders (3-9) and their bottom-five (28th) scoring defense at U.S. Bank Stadium.

• Game Preview: Washington Commanders at Minnesota Vikings
• Projected Favorite: Vikings (52.50% win probability)
• Spread: Minnesota (-1.5)
• Total: 42.5 -- Over: (-108) | Under: (-112)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Minnesota vs. Washington with FanDuel Sportsbook.

Browns vs. Titans

Two struggling offenses will match up on Dec. 7 at 1 p.m. ET, when the Cleveland Browns (3-9) host the Tennessee Titans (1-11) at Huntington Bank Field. The Browns sport the 29th-ranked scoring offense in the league (16.2 points per game), while the Titans rank dead last at 14.2 points per game.

• Game Preview: Tennessee Titans at Cleveland Browns
• Projected Favorite: Browns (72.33% win probability)
• Spread: Cleveland (-3.5)
• Total: 33.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Cleveland vs. Tennessee with FanDuel Sportsbook.

Bills vs. Bengals

The Buffalo Bills (8-4), who have the NFL's fifth-ranked scoring offense (28.1 points per game), will try to exploit the Cincinnati Bengals' (4-8) worst-ranked scoring defense (31.2 points allowed per contest) when the squads match up at Highmark Stadium on Sunday, Dec. 7 at 1 p.m. ET.

• Game Preview: Cincinnati Bengals at Buffalo Bills
• Projected Favorite: Bills (73.11% win probability)
• Spread: Buffalo (-5.5)
• Total: 52.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Buffalo vs. Cincinnati with FanDuel Sportsbook.

Buccaneers vs. Saints

When the Tampa Bay Buccaneers (7-5) and the New Orleans Saints (2-10) match up on Sunday, Dec. 7 at 1 p.m. ET, the Buccaneers will be looking to follow up their recent victory over the Cardinals with another win, and the Saints will be trying to bounce back from a loss to the Dolphins.

• Game Preview: New Orleans Saints at Tampa Bay Buccaneers
• Projected Favorite: Buccaneers (69.93% win probability)
• Spread: Tampa Bay (-8.5)
• Total: 42.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Tampa Bay vs. New Orleans with FanDuel Sportsbook.

Jaguars vs. Colts

One of the top running backs in football will be on display when Jonathan Taylor and the Indianapolis Colts (8-4) visit the Jacksonville Jaguars (8-4) on Sunday, December 7, 2025.

• Game Preview: Indianapolis Colts at Jacksonville Jaguars
• Projected Favorite: Colts (57.70% win probability)
• Spread: Indianapolis (-1.5)
• Total: 47.5 -- Over: (-112) | Under: (-108)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Jacksonville vs. Indianapolis with FanDuel Sportsbook.

Jets vs. Dolphins

De'Von Achane will lead the Miami Dolphins (5-7) into their game against the New York Jets (3-9) at MetLife Stadium on Sunday at 1 p.m. ET.

• Game Preview: Miami Dolphins at New York Jets
• Projected Favorite: Dolphins (59.82% win probability)
• Spread: Miami (-3)
• Total: 41.5 -- Over: (+100) | Under: (-122)
• Time: 1 p.m. ET
• Channel: CBS

Bet on New York vs. Miami with FanDuel Sportsbook.

Falcons vs. Seahawks

On Sunday at 1 p.m. ET, a pair of star pass-catchers will be on display when Jaxon Smith-Njigba and the Seattle Seahawks (9-3) visit Drake London and the Atlanta Falcons (4-8).

• Game Preview: Seattle Seahawks at Atlanta Falcons
• Projected Favorite: Seahawks (65.71% win probability)
• Spread: Seattle (-7.5)
• Total: 44.5 -- Over: (-108) | Under: (-112)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Atlanta vs. Seattle with FanDuel Sportsbook.

Ravens vs. Steelers

Derrick Henry will lead the Baltimore Ravens (6-6) into their game versus the Pittsburgh Steelers (6-6) at M&T Bank Stadium on Sunday at 1 p.m. ET.

• Game Preview: Pittsburgh Steelers at Baltimore Ravens
• Projected Favorite: Ravens (70.33% win probability)
• Spread: Baltimore (-5.5)
• Total: 43.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Baltimore vs. Pittsburgh with FanDuel Sportsbook.

Raiders vs. Broncos

With an offense that ranks 31st in the league at 14.9 points per game, the Las Vegas Raiders (2-10) have a tough road ahead against the Denver Broncos (10-2) and their fourth-ranked defense (18.2 points surrendered per contest). The two squads square off at 4:05 p.m. ET on Dec. 7.

• Game Preview: Denver Broncos at Las Vegas Raiders
• Projected Favorite: Broncos (78.49% win probability)
• Spread: Denver (-7.5)
• Total: 40.5 -- Over: (-108) | Under: (-112)
• Time: 4:05 p.m. ET
• Channel: CBS

Bet on Las Vegas vs. Denver with FanDuel Sportsbook.

Packers vs. Bears

On Sunday at 4:25 p.m. ET, a pair of the best offensive performers in football will be featured when running back Josh Jacobs and the Green Bay Packers (8-3-1) host quarterback Caleb Williams and the Chicago Bears (9-3).

• Game Preview: Chicago Bears at Green Bay Packers
• Projected Favorite: Packers (70.27% win probability)
• Spread: Green Bay (-6.5)
• Total: 44.5 -- Over: (-114) | Under: (-106)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Green Bay vs. Chicago with FanDuel Sportsbook.

Cardinals vs. Rams

The Los Angeles Rams (9-3), who were taken down by the Panthers in their previous contest, visit the Arizona Cardinals (3-9) at State Farm Stadium on Dec. 7 at 4:25 p.m. ET. The Cardinals took the L against the Buccaneers in their last game.

• Game Preview: Los Angeles Rams at Arizona Cardinals
• Projected Favorite: Rams (69.62% win probability)
• Spread: Los Angeles (-8.5)
• Total: 48.5 -- Over: (-105) | Under: (-115)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Arizona vs. Los Angeles with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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