Monday’s MLB Strikeout Props - Sept. 21

Will Zebby Matthews strike out more than 4.5 batters? Can Blade Tidwell exceed 3.5 strikeouts? See their odds and more strikeout prop odds for all pitchers in MLB play on Sept. 21, in the article below.

Today's MLB Strikeout Props

Minnesota Twins at San Francisco Giants

• Zebby Matthews (Twins): Over/Under 4.5 Ks (Over -108, Under -118) | 2026 Stats: 4.9 strikeouts per game in 22 appearances
• Blade Tidwell (Giants): Over/Under 3.5 Ks (Over -158, Under +124) | 2026 Stats: 2.6 strikeouts per game in 16 appearances