Friday’s MLB Odds, Betting Lines and Predictions - May 16

In a Friday MLB schedule that features plenty of thrilling contests, the New York Mets versus the New York Yankees is a game to watch. For predictions on every game on the slate, check out the article below.

Today's MLB Odds and Predictions

Chicago White Sox at Chicago Cubs Odds, Lines & Predictions

Game Info

• When: 2:20 p.m. ET
• Where: Wrigley Field
• TV Channel: MLB Network, MARQ and CHSN
• Probable Pitchers: Cade Horton vs. Shane Smith
• Records: Cubs (25-19), White Sox (14-30)
• Cubs Moneyline Odds: -225
• White Sox Moneyline Odds: +188

numberFire Prediction

• numberFire Predicted Favorite: Cubs
• Cubs Win Probability: 61.86%
• White Sox Win Probability: 38.14%

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Cleveland Guardians at Cincinnati Reds Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Great American Ball Park
• TV Channel: FDSOH and CLEG
• Probable Pitchers: Brady Singer vs. Tanner Bibee
• Records: Reds (21-24), Guardians (25-18)
• Guardians Moneyline Odds: -118
• Reds Moneyline Odds: +100

numberFire Prediction

• numberFire Predicted Favorite: Reds
• Reds Win Probability: 55.84%
• Guardians Win Probability: 44.16%

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Pittsburgh Pirates at Philadelphia Phillies Odds, Lines & Predictions

Game Info

• When: 6:45 p.m. ET
• Where: Citizens Bank Park
• TV Channel: NBCS-PH and SportsNet PT
• Probable Pitchers: Ranger Suarez vs. Andrew Heaney
• Records: Phillies (25-18), Pirates (15-29)
• Phillies Moneyline Odds: -220
• Pirates Moneyline Odds: +184

numberFire Prediction

• numberFire Predicted Favorite: Phillies
• Phillies Win Probability: 65.67%
• Pirates Win Probability: 34.33%

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Washington Nationals at Baltimore Orioles Odds, Lines & Predictions

Game Info

• When: 7:05 p.m. ET
• Where: Oriole Park at Camden Yards
• TV Channel: MASN and MASN2
• Probable Pitchers: Cade Povich vs. MacKenzie Gore
• Records: Orioles (15-27), Nationals (18-27)
• Orioles Moneyline Odds: -108
• Nationals Moneyline Odds: -108

numberFire Prediction

• numberFire Predicted Favorite: Orioles
• Orioles Win Probability: 52.40%
• Nationals Win Probability: 47.60%

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New York Mets at New York Yankees Odds, Lines & Predictions

Game Info

• When: 7:05 p.m. ET
• Where: Yankee Stadium
• TV Channel: YES and WPIX
• Probable Pitchers: Carlos Rodon vs. Tylor Megill
• Records: Yankees (25-18), Mets (28-16)
• Yankees Moneyline Odds: -134
• Mets Moneyline Odds: +116

numberFire Prediction

• numberFire Predicted Favorite: Yankees
• Yankees Win Probability: 51.90%
• Mets Win Probability: 48.10%

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Detroit Tigers at Toronto Blue Jays Odds, Lines & Predictions

Game Info

• When: 7:07 p.m. ET
• Where: Rogers Centre
• TV Channel: MLB Network, SN1 and FDSDET
• Probable Pitchers: Bowden Francis vs. Jack Flaherty
• Records: Blue Jays (21-22), Tigers (29-15)
• Tigers Moneyline Odds: -126
• Blue Jays Moneyline Odds: +108

numberFire Prediction

• numberFire Predicted Favorite: Tigers
• Tigers Win Probability: 59.47%
• Blue Jays Win Probability: 40.53%

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Tampa Bay Rays at Miami Marlins

Game Info

• When: 7:10 p.m. ET
• Where: loanDepot park
• TV Channel: FDSFL and FDSSUN
• Probable Pitchers: Max Meyer vs. Taj Bradley
• Records: Marlins (16-26), Rays (20-23)

numberFire Prediction

• numberFire Predicted Favorite: Rays
• Rays Win Probability: 53.29%
• Marlins Win Probability: 46.71%

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Atlanta Braves at Boston Red Sox Odds, Lines & Predictions

Game Info

• When: 7:10 p.m. ET
• Where: Fenway Park
• TV Channel: MLB Network, NESN and FDSSO
• Probable Pitchers: Garrett Crochet vs. Chris Sale
• Records: Red Sox (22-23), Braves (22-22)
• Red Sox Moneyline Odds: -120
• Braves Moneyline Odds: +102

numberFire Prediction

• numberFire Predicted Favorite: Red Sox
• Red Sox Win Probability: 52.40%
• Braves Win Probability: 47.60%

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St. Louis Cardinals at Kansas City Royals Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: Kauffman Stadium
• TV Channel: FDSKC and FDSMW
• Probable Pitchers: Cole Ragans vs. Andre Pallante
• Records: Royals (25-20), Cardinals (24-20)
• Royals Moneyline Odds: -162
• Cardinals Moneyline Odds: +136

numberFire Prediction

• numberFire Predicted Favorite: Royals
• Royals Win Probability: 57.40%
• Cardinals Win Probability: 42.60%

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Houston Astros at Texas Rangers Odds, Lines & Predictions

Game Info

• When: 8:05 p.m. ET
• Where: Globe Life Field
• TV Channel: Apple TV+
• Probable Pitchers: Nathan Eovaldi vs. Lance McCullers
• Records: Rangers (24-21), Astros (22-21)
• Rangers Moneyline Odds: -174
• Astros Moneyline Odds: +146

numberFire Prediction

• numberFire Predicted Favorite: Rangers
• Rangers Win Probability: 58.04%
• Astros Win Probability: 41.96%

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Minnesota Twins at Milwaukee Brewers Odds, Lines & Predictions

Game Info

• When: 8:10 p.m. ET
• Where: American Family Field
• TV Channel: FDSWI and MNNT
• Probable Pitchers: Chad Patrick vs. Joe Ryan
• Records: Brewers (21-23), Twins (24-20)
• Twins Moneyline Odds: -110
• Brewers Moneyline Odds: -106

numberFire Prediction

• numberFire Predicted Favorite: Twins
• Twins Win Probability: 54.15%
• Brewers Win Probability: 45.85%

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Seattle Mariners at San Diego Padres Odds, Lines & Predictions

Game Info

• When: 9:40 p.m. ET
• Where: PETCO Park
• TV Channel: Apple TV+
• Probable Pitchers: Stephen Kolek vs. Logan Evans
• Records: Padres (27-15), Mariners (23-19)
• Padres Moneyline Odds: -148
• Mariners Moneyline Odds: +126

numberFire Prediction

• numberFire Predicted Favorite: Padres
• Padres Win Probability: 56.51%
• Mariners Win Probability: 43.49%

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Colorado Rockies at Arizona Diamondbacks Odds, Lines & Predictions

Game Info

• When: 9:40 p.m. ET
• Where: Chase Field
• TV Channel: ARID and COLR
• Probable Pitchers: Corbin Burnes vs. Carson Palmquist
• Records: Diamondbacks (23-21), Rockies (7-36)
• Diamondbacks Moneyline Odds: -405
• Rockies Moneyline Odds: +320

numberFire Prediction

• numberFire Predicted Favorite: Diamondbacks
• Diamondbacks Win Probability: 71.74%
• Rockies Win Probability: 28.26%

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Los Angeles Angels at Los Angeles Dodgers Odds, Lines & Predictions

Game Info

• When: 10:10 p.m. ET
• Where: Dodger Stadium
• TV Channel: MLB Network, SportsNet LA and FDSW
• Probable Pitchers: Dustin May vs. Jack Kochanowicz
• Records: Dodgers (28-15), Angels (17-25)
• Dodgers Moneyline Odds: -300
• Angels Moneyline Odds: +245

numberFire Prediction

• numberFire Predicted Favorite: Dodgers
• Dodgers Win Probability: 66.79%
• Angels Win Probability: 33.21%

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Athletics at San Francisco Giants Odds, Lines & Predictions

Game Info

• When: 10:15 p.m. ET
• Where: Oracle Park
• TV Channel: MLB Network, NBCS-BA and NBCS-CA
• Probable Pitchers: Logan Webb vs. JP Sears
• Records: Giants (25-19), Athletics (22-21)
• Giants Moneyline Odds: -172
• Athletics Moneyline Odds: +144

numberFire Prediction

• numberFire Predicted Favorite: Giants
• Giants Win Probability: 63.99%
• Athletics Win Probability: 36.01%

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All MLB win probability predictions and picks are according to numberFire.