Missouri vs Drake Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament First Round

An opening-round NCAA Tournament matchup will see the No. 6-seed Missouri Tigers (22-11) hit the court against the No. 11 seed Drake Bulldogs (30-3) on Thursday at INTRUST Bank Arena. The matchup starts at 7:35 p.m. ET, on truTV.
Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.
Missouri vs. Drake Game Info and Odds
- Game day: Thursday, March 20, 2025
- Game time: 7:35 p.m. ET
- TV channel: truTV
- Location: Wichita, Kansas
- Arena: INTRUST Bank Arena
Missouri vs. Drake Picks and Prediction
All college basketball win probability predictions and picks are according to numberFire.
Prediction: Missouri win (55.8%)
Take a look at some betting trends and insights for Missouri (-6.5) versus Drake on Thursday. The over/under is set at 132.5 points for this game.
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Missouri vs. Drake: ATS Betting Stats and Trends
- Missouri has won 18 games against the spread this season, while failing to cover 14 times.
- Drake has put together a 16-13-0 ATS record so far this season.
- Missouri (6-7) covers a lower percentage of games when it is favored by 6.5 points or more this season (46.2%) than Drake (1-0) does as a 6.5+-point underdog (100%).
- Against the spread, the Tigers have fared better at home, covering 11 times in 19 home games, and five times in 10 road games.
- The Bulldogs' winning percentage against the spread at home is .357 (5-9-0). On the road, it is .600 (6-4-0).
Missouri vs. Drake: Moneyline Betting Stats
- Missouri has been the moneyline favorite in 21 games this season and has come away with the win 16 times (76.2%) in those contests.
- The Tigers have yet to lose in 10 games when named as moneyline favorite of -275 or better.
- Drake has won all six of the games it has been listed as the moneyline underdog this season.
- The Bulldogs have played as a moneyline underdog of +225 or longer in just one game this season, which they won.
- Bookmakers have implied with the moneyline set for this matchup that Missouri has a 73.3% chance of pulling out a win.
Missouri vs. Drake Head-to-Head Comparison
- Missouri outscores opponents by 10.7 points per game (scoring 84.5 per game to rank ninth in college basketball while giving up 73.8 per outing to rank 233rd in college basketball) and has a +350 scoring differential overall.
- Mark Mitchell paces Missouri, recording 14.1 points per game (369th in the country).
- Drake is outscoring opponents by 11.7 points per game, with a +385 scoring differential overall. It puts up 70.1 points per game (279th in college basketball) and gives up 58.4 per outing (first in college basketball).
- Bennett Stirtz's 19.1 points per game leads Drake and ranks 41st in the country.
- The Tigers rank 222nd in the nation at 31.2 rebounds per game. That's 1.7 more than the 29.5 their opponents average.
- Josh Gray's 5.3 rebounds per game lead the Tigers and rank 509th in college basketball play.
- The Bulldogs come out on top in the rebound battle by an average of 6.9 boards. They are grabbing 28.8 rebounds per game (330th in college basketball) compared to their opponents' 21.9.
- Cam Manyawu's 5.4 rebounds per game lead the Bulldogs and rank 482nd in the nation.
- Missouri ranks eighth in college basketball with 106.8 points scored per 100 possessions, and 171st in college basketball defensively with 93.4 points conceded per 100 possessions.
- The Bulldogs score 104.3 points per 100 possessions (24th in college basketball), while allowing 86.9 points per 100 possessions (30th in college basketball).
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