Memphis vs South Florida Prediction, Odds, Picks, Best Bets for Week 11 2026

The Memphis Tigers will take on the South Florida Bulls in college football action on Thursday.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Memphis vs South Florida Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Memphis: (-172) | South Florida: (+142)
• Spread: Memphis: -4.5 (-105) | South Florida: +4.5 (-115)
• Total: 50.5 -- Over: (-110) | Under: (-110)

Memphis vs South Florida Betting Trends

• Against the spread, Memphis is 5-4-0 this year.
• For the year, Memphis is 4-3 as 4.5-point or better favorites.
• Out of nine Memphis games so far this year, six have gone over the total.
• Against the spread, South Florida is 4-5-0 this year.
• South Florida is winless ATS (0-1) when playing as at least 4.5-point underdogs this year.
• There have been three South Florida games (out of nine) that hit the over this season.

Memphis vs South Florida Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (75.9%)

Memphis vs South Florida Point Spread

South Florida is a 4.5-point underdog against Memphis. South Florida is -115 to cover the spread, and Memphis is -105.

Memphis vs South Florida Over/Under

A combined point total of 50.5 has been set for Memphis-South Florida on Nov. 12, with the over at -110 and the under at -110.

Memphis vs South Florida Moneyline

Looking at the moneyline for Memphis-South Florida, Memphis is the favorite at -172, and South Florida is +142.

Memphis vs. South Florida Points Insights

Memphis vs. South Florida Game Info

• Game day: Thursday, November 12, 2026
• Game time: 8 p.m. ET
• TV channel: ESPN
• Location: Tampa, Florida
• Stadium: Raymond James Stadium

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Check out even more in-depth Memphis vs. South Florida analysis on FanDuel Research.