Memphis vs East Carolina Prediction, Odds, Picks, Best Bets for Week 8 2026

In college football action on Thursday, the Memphis Tigers take on the East Carolina Pirates.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Memphis vs East Carolina Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Memphis: (-429) | East Carolina: (+330)
• Spread: Memphis: -10.5 (-102) | East Carolina: +10.5 (-120)
• Total: 54.5 -- Over: (-105) | Under: (-115)

Memphis vs East Carolina Betting Trends

• Against the spread, Memphis is 4-3-0 this year.
• As 10.5-point favorites or more, Memphis is 3-1 against the spread.
• There have been four Memphis games (of seven) that went over the total this year.
• East Carolina owns two wins against the spread this season.
• East Carolina is winless ATS (0-1) when playing as at least 10.5-point underdogs this season.
• One of East Carolina's six games has hit the over.

Memphis vs East Carolina Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (82.6%)

Memphis vs East Carolina Point Spread

East Carolina is listed as an underdog by 10.5 points (-120 odds), and Memphis, the favorite, is -102 to cover.

Memphis vs East Carolina Over/Under

Memphis versus East Carolina on Oct. 22 has an over/under of 54.5 points, with the over -105 and the under -115.

Memphis vs East Carolina Moneyline

Looking at the moneyline for East Carolina-Memphis, East Carolina is the underdog at +330, and Memphis is -429.

Memphis vs. East Carolina Points Insights

Memphis vs. East Carolina Game Info

• Game day: Thursday, October 22, 2026
• Game time: 7:30 p.m. ET
• TV channel: ESPN2
• Location: Memphis, Tennessee
• Stadium: Simmons Bank Liberty Stadium

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Check out even more in-depth Memphis vs. East Carolina analysis on FanDuel Research.