Marquette vs Villanova Basketball Prediction, Odds, Picks, Best Bets for February 21

The No. 16 Marquette Golden Eagles (20-6, 11-4 Big East) visit the Villanova Wildcats (15-12, 8-8 Big East) in Big East action at Wells Fargo Center, tipping off at 7:00 PM ET on Friday, February 21, 2025.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Marquette vs. Villanova Game Info and Odds

• Game day: Friday, February 21, 2025
• Game time: 7:00 PM ET
• TV channel: Fox Sports 1
• Location: Philadelphia, Pennsylvania
• Arena: Wells Fargo Center

Before making an informed wager on Marquette-Villanova outing (in which Marquette is a 1.5-point favorite and the total has been set at 141.5 points), below are a few betting insights and trends for Friday's game.

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Marquette vs. Villanova: ATS Betting Stats and Trends

• Marquette has put together a 12-14-0 ATS record so far this year.
• Villanova has won 14 games against the spread this season, while failing to cover 13 times.
• As a 1.5-point underdog or more in 2024-25, Villanova is 5-4 against the spread compared to the 11-11 ATS record Marquette puts up as a 1.5-point favorite.
• The Golden Eagles have covered the spread in a higher percentage of their home games than away games. They have covered seven times in 15 opportunities when playing at home, and they've covered four times in 10 opportunities on the road.
• In 2024-25 against the spread, the Wildcats have a better winning percentage at home (.600, 9-6-0 record) than on the road (.333, 3-6-0).
• Against the spread, in conference games, Marquette is 5-10-0 this year.
• Villanova's Big East record against the spread is 8-8-0.

Marquette vs. Villanova: Moneyline Betting Stats

• Marquette has come away with 17 wins in the 19 contests it has been listed as the moneyline favorite in this season.
• This season, the Golden Eagles have been victorious 17 times in 19 chances when named as a favorite of at least -128 or better on the moneyline.
• Villanova has been the underdog on the moneyline eight total times this season. Villanova has finished 2-6 in those games.
• The Wildcats have a 2-6 record (winning just 25% of their games) when they have played as a moneyline underdog of +106 or longer.
• The moneyline set for this matchup implies Marquette has a 56.1% chance of walking away with the win.

Marquette vs. Villanova Head-to-Head Comparison

• Marquette is outscoring opponents by 10.2 points per game with a +267 scoring differential overall. It puts up 77.3 points per game (93rd in college basketball) and gives up 67.1 per contest (52nd in college basketball).
• Kam Jones is 43rd in the country with a team-high 19 points per game.
• Villanova's +171 scoring differential (outscoring opponents by 6.4 points per game) is a result of putting up 74.3 points per game (180th in college basketball) while giving up 67.9 per outing (65th in college basketball).
• Eric Dixon's team-leading 22.9 points per game rank him first in the country.
• The Golden Eagles average 30.8 rebounds per game (258th in college basketball) compared to the 31.8 of their opponents.
• David Joplin is 505th in college basketball play with 5.3 rebounds per game to lead the Golden Eagles.
• The Wildcats grab 30.7 rebounds per game (266th in college basketball) while conceding 26.9 per outing to opponents. They outrebound opponents by 3.8 boards per game.
• Wooga Poplar leads the Wildcats with 6.5 rebounds per game (233rd in college basketball).
• Marquette's 100.2 points per 100 possessions on offense rank 78th in college basketball, and the 86.9 points it allows per 100 possessions rank 43rd in college basketball.
• The Wildcats rank 26th in college basketball averaging 103.8 points per 100 possessions on offense, and defensively are 235th, allowing 94.9 points per 100 possessions.

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