Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 25

Odds updated as of 10:12 a.m.

The MLB schedule on Monday includes the Seattle Mariners facing the San Diego Padres.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Mariners vs Padres Game Info

• Seattle Mariners (70-61) vs. San Diego Padres (74-57)
• Date: Monday, August 25, 2025
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: ROOT Sports NW and SDPA

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-126) | SD: (+108)
• Spread: SEA: -1.5 (+162) | SD: +1.5 (-196)
• Total: 8 -- Over: (-114) | Under: (-106)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: Bryce Miller (Mariners) - 2-5, 5.87 ERA vs JP Sears (Padres) - 8-10, 4.94 ERA

The Mariners will call on Bryce Miller (2-5) versus the Padres and JP Sears (8-10). Miller's team is 4-7-0 against the spread in his starts this season. Miller's team has won 33.3% of his starts when they are favored on the moneyline (2-4). The Padres have a 13-11-0 ATS record in Sears' 24 starts that had a set spread. The Padres are 5-11 in Sears' 16 starts this season that they were the underdog on the moneyline.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (54%)

Mariners vs Padres Moneyline

• San Diego is a +108 underdog on the moneyline, while Seattle is a -126 favorite at home.

Mariners vs Padres Spread

• The Padres are at +1.5 on the runline against the Mariners. The Padres are -196 to cover the spread, and the Mariners are +162.

Mariners vs Padres Over/Under

• The over/under for Mariners-Padres on Aug. 25 is 8. The over is -114, and the under is -106.

Bet on Seattle Mariners vs. San Diego Padres on FanDuel today!

Mariners vs Padres Betting Trends

• The Mariners have won in 49, or 57%, of the 86 contests they have been named as odds-on favorites in this year.
• Seattle has a record of 40-25 in contests when sportsbooks favor them by -126 or more on the moneyline.
• The Mariners and their opponents have gone over in 66 of their 126 games with a total set by sportsbooks this season.
• The Mariners have an against the spread mark of 53-73-0 in 126 games with a line this season.
• The Padres have put together a 29-29 record in games they were listed as the moneyline underdog (winning 50% of those games).
• San Diego has gone 21-23 when it has played as a moneyline underdog with odds of +108 or longer (47.7%).
• The Padres have combined with opponents to go over the total 55 times this season for a 55-71-3 record against the over/under.
• The Padres have a 73-56-0 record against the spread this season (covering 56.6% of the time).

Mariners Player Leaders

• Cal Raleigh leads Seattle in total hits (119) this season while batting .247 with 68 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .593.
• Among qualified hitters in MLB, his batting average ranks 104th, his on-base percentage ranks 37th, and he is third in slugging.
• Julio Rodriguez has hit 25 homers this season while driving in 73 runs. He's batting .259 this season and slugging .459 with an on-base percentage of .313.
• He ranks 76th in batting average, 110th in on-base percentage and 55th in slugging in the majors.
• Josh Naylor has 125 hits this season and has a slash line of .282/.347/.449.
• Naylor has picked up a hit in three games in a row. During his last five outings he is hitting .188 with a double, a home run, a walk and three RBIs.
• Eugenio Suarez is batting .236 with a .307 OBP and 98 RBI for Seattle this season.

Padres Player Leaders

• Manny Machado has put up a team-high slugging percentage (.480) and leads the Padres in hits (147). He's batting .292 and with an on-base percentage of .354.
• Including all qualifying hitters, he ranks 14th in batting average, while his on-base percentage ranks 33rd and he is 33rd in slugging.
• Fernando Tatis Jr. has a .373 on-base percentage to pace his team. He has a batting average of .264 while slugging .429.
• He is 57th in batting average, 12th in on-base percentage and 80th in slugging percentage in the majors.
• Luis Arraez has 28 doubles, four triples, six home runs and 26 walks while hitting .285.
• Xander Bogaerts is hitting .260 with 29 doubles, 10 home runs and 48 walks.

Mariners vs Padres Head to Head

• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/7/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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