Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 17

Odds updated as of 4:11 a.m.

The MLB schedule on Sunday includes the Seattle Mariners facing the San Diego Padres.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Mariners vs Padres Game Info

• Seattle Mariners (22-25) vs. San Diego Padres (27-18)
• Date: Sunday, May 17, 2026
• Time: 7:20 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Peacock

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-158) | SD: (+134)
• Spread: SEA: -1.5 (+132) | SD: +1.5 (-160)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 5-2, 2.84 ERA vs Lucas Giolito (Padres) - 0-0, 0.00 ERA

The Mariners will give the nod to George Kirby (5-2, 2.84 ERA), who is eyeing win No. 6 on the season, and the Padres will counter with Lucas Giolito. Kirby's team is 5-4-0 against the spread in his starts this season. Kirby's team has won 66.7% of his starts when they are favored on the moneyline (6-3). Giolito and his team were underdogs on the moneyline every time he pitched a season ago.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (60.7%)

Mariners vs Padres Moneyline

• The Mariners vs Padres moneyline has Seattle as a -158 favorite, while San Diego is a +134 underdog on the road.

Mariners vs Padres Spread

• The Mariners are hosting the Padres and are favored by 1.5 runs (+132 to cover) on the runline. San Diego is -160 to cover.

Mariners vs Padres Over/Under

• The over/under for Mariners-Padres on May 17 is 7.5. The over is -110, and the under is -110.

Bet on Seattle Mariners vs. San Diego Padres on FanDuel today!

Mariners vs Padres Betting Trends

• The Mariners have been chosen as favorites in 43 games this year and have walked away with the win 21 times (48.8%) in those games.
• This year Seattle has won six of 11 games when listed as at least -158 on the moneyline.
• The Mariners and their opponents have gone over the total this season in 21 of their 47 opportunities.
• In 47 games with a line this season, the Mariners have a mark of 17-30-0 against the spread.
• The Padres have put together a 10-8 record in games they were listed as the moneyline underdog (winning 55.6% of those games).
• San Diego has played as a moneyline underdog of +134 or longer in just one game this season, which it won.
• The Padres have played in 45 games with an over/under set, and have combined with opponents to go over the total 19 times (19-25-1).
• The Padres have a 25-20-0 record ATS this season (covering 55.6% of the time).

Mariners Player Leaders

• Randy Arozarena has 52 hits and an OBP of .394 to go with a slugging percentage of .453. All three of those stats lead Seattle hitters this season. He has a .306 batting average, as well.
• Among all qualifying batters in MLB, his batting average ranks 16th, his on-base percentage ranks 13th, and he is 52nd in slugging.
• Arozarena hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .474 with two doubles, a home run, three walks and four RBIs.
• J.P. Crawford is batting .217 with four doubles, six home runs and 29 walks. He's slugging .377 with an on-base percentage of .361.
• His batting average ranks 139th among qualified players, his on-base percentage 43rd, and his slugging percentage 109th.
• Julio Rodriguez is batting .255 with a .415 slugging percentage and 20 RBI this year.
• Josh Naylor has five home runs, 20 RBI and a batting average of .253 this season.
• Naylor brings a five-game hitting streak into this game. During his last five outings he is hitting .286 with a double and three walks.

Padres Player Leaders

• Xander Bogaerts has 42 hits with a .333 on-base percentage and a .413 slugging percentage, all club-bests for the Padres. He's batting .263.
• Including all qualifying players in MLB, he is 63rd in batting average, 81st in on-base percentage and 70th in slugging percentage.
• Gavin Sheets is batting .244 with nine doubles, seven home runs and 12 walks. He's slugging .488 with an on-base percentage of .316.
• Manny Machado is batting .182 with four doubles, six home runs and 22 walks.
• Jackson Merrill is hitting .205 with eight doubles, four home runs and 15 walks.

Mariners vs Padres Head to Head

• 5/16/2026: 7-4 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/15/2026: 2-0 SD (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/16/2026: 5-2 SD (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/15/2026: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/14/2026: 4-1 SD (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/27/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/26/2025: 7-6 SD (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/25/2025: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)

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