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LSU vs. Ole Miss Picks: Prediction, Props and Best Bets

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LSU vs. Ole Miss Picks: Prediction, Props and Best Bets

LSU vs Mississippi Picks in Summary

  • Over 57.5 Points (-110)
  • Kewan Lacy 80+ Rushing Yards (-115)

Even within a single college football game, betting markets are abundant.

You've got everything from spreads and totals to — for some games — touchdown scorers and player props at your disposal. It can be a lot to sort through.

Using the college football odds at FanDuel Sportsbook as a guide, here are the best bets for this game.

All college football odds come from FanDuel Sportsbook and may change after this article is published.

LSU vs Ole Miss College Football Prediction and Picks

Over 57.5 Points (-110)

Total Points

Over
Sep 19 11:30pm UTCMore odds in Sportsbook

This matchup has the ingredients for a high-scoring game, which is why the over/under is where it is. But I think the market may still be a little short.

The LSU Tigers have scored 51 and 45 points in their first two games, averaging 48.0 points per contest, while the Mississippi Rebels are averaging 41.0 points per game through two games. The Rebels have also produced 314.5 passing yards per game with Trinidad Chambliss completing 70.97% of his passes.

Ole Miss has already played one shootout this season, beating Louisville 41-38, and the Rebels have generated 454 total yards per game. LSU's offense has been just as explosive, so even though both teams have capable defenses, I like their offensive ceilings to push this game over 57.5.

Kewan Lacy 80+ Rushing Yards (-115)

Kewan Lacy - Alt Rushing Yds
Kewan Lacy 80+ Yards

Kewan Lacy to run for at least 80 yards is my favorite player prop for this headline clash.

Lacy is a huge piece of the Rebels’ offensive attack, and the matchup sets up well for a shootout. As we just mentioned, LSU-Ole Miss carries a 57.5-point total, giving this game considerable scoring potential.

A year ago, Lacy averaged 104.5 rushing yards per game, and he should be primed for a big workload after carrying the rock only 13 times last week in Ole Miss’ 41-9 win.


College Football Betting FAQ

What are the most common college football bets?

The most common college football bets are the point spread, moneyline, and game total. Bettors can also wager on player props, team totals, alternate spreads, and futures such as conference champions or the national championship winner.

How does the point spread work in college football betting?

The point spread gives one team a handicap to create a more even betting market. If a team is listed at -7.5, it must win by at least eight points for a spread bet on that team to cash. A team listed at +7.5 can lose by seven points or fewer — or win outright — and still cover the spread.

What does over/under mean in college football?

An over/under, also called a game total, is a wager on the combined number of points scored by both teams. Bettors can choose whether the final score will finish over or under the sportsbook's posted total.

What should you consider before betting on college football?

Matchups, quarterback play, offensive and defensive efficiency, injuries, pace, home-field advantage, and coaching tendencies can all be important.


Get a 100% Profit Boost Token to use on ANY wager for the LSU @ Ole Miss College Football Game taking place on September 19th, 2026! See here for full terms and conditions. Learn about today's other offers at FanDuel Sportsbook Promos.

Looking for the latest college football odds? Head over to FanDuel Sportsbook and check out all of the college football betting options.

You can also check out our How to Bet on College Football guide.

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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.

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