LSU vs Mississippi State Prediction, Odds, Picks, Best Bets for Week 7 2026

The LSU Tigers versus the Mississippi State Bulldogs is on the college football schedule for Saturday.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

LSU vs Mississippi State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LSU: (-877) | Mississippi State: (+580)
• Spread: LSU: -16.5 (-122) | Mississippi State: +16.5 (100)
• Total: 56.5 -- Over: (-105) | Under: (-115)

LSU vs Mississippi State Betting Trends

• LSU has won twice against the spread this season.
• LSU has no wins ATS (0-2) as a 16.5-point favorite or greater this season.
• There have been four LSU games (of six) that went over the total this season.
• Against the spread, Mississippi State is 4-1-0 this year.
• There have been three Mississippi State games (out of five) that hit the over this year.

LSU vs Mississippi State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (86.1%)

LSU vs Mississippi State Point Spread

Mississippi State is a 16.5-point underdog against LSU. Mississippi State is +100 to cover the spread, and LSU is -122.

LSU vs Mississippi State Over/Under

The over/under for the LSU versus Mississippi State game on Oct. 17 has been set at 56.5, with -105 odds on the over and -115 odds on the under.

LSU vs Mississippi State Moneyline

Looking at the moneyline for LSU-Mississippi State, LSU is the favorite at -877, and Mississippi State is +580.

LSU vs. Mississippi State Points Insights

LSU vs. Mississippi State Game Info

• Game day: Saturday, October 17, 2026
• Game time: 12 p.m. ET
• TV channel: ESPN
• Location: Baton Rouge, Louisiana
• Stadium: Tiger Stadium

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Check out even more in-depth LSU vs. Mississippi State analysis on FanDuel Research.