Iowa State vs Cincinnati Prediction, Odds, Picks, Best Bets for Week 11 2026

College football's Saturday slate includes the Iowa State Cyclones taking on the Cincinnati Bearcats.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding today's NCAA football betting odds.

Iowa State vs Cincinnati Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Iowa State: (-146) | Cincinnati: (+122)
• Spread: Iowa State: -2.5 (-125) | Cincinnati: +2.5 (105)
• Total: 60.5 -- Over: (-110) | Under: (-110)

Iowa State vs Cincinnati Betting Trends

• Iowa State has four wins in nine games against the spread this year.
• As at least a 2.5-point favorite, Iowa State has two wins ATS (2-1).
• Out of nine Iowa State games so far this year, five have hit the over.
• Cincinnati has beaten the spread five times in nine games.
• Cincinnati is 3-2 as 2.5-point or bigger underdogs in 2026.
• Cincinnati has played nine games this season, and six of them have gone over the total.

Iowa State vs Cincinnati Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Bearcats win (50.3%)

Iowa State vs Cincinnati Point Spread

Iowa State is a 2.5-point favorite against Cincinnati. Iowa State is -125 to cover the spread, and Cincinnati is +105.

Iowa State vs Cincinnati Over/Under

A combined point total of 60.5 has been set for Iowa State-Cincinnati on Nov. 14, with the over at -110 and the under at -110.

Iowa State vs Cincinnati Moneyline

The Iowa State vs Cincinnati moneyline has Iowa State as a -146 favorite, while Cincinnati is a +122 underdog.

Iowa State vs. Cincinnati Points Insights

Iowa State vs. Cincinnati Game Info

• Game day: Saturday, November 14, 2026
• Game time: 12 p.m. ET
• TV channel: TNT
• Location: Ames, Iowa
• Stadium: Jack Trice Stadium

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Check out even more in-depth Iowa State vs. Cincinnati analysis on FanDuel Research.