LSU vs Kentucky Prediction, Odds, Picks, Best Bets for Week 6 2026

The LSU Tigers will face the Kentucky Wildcats in college football action on Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

LSU vs Kentucky Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LSU: (-334) | Kentucky: (+265)
• Spread: LSU: -8.5 (-110) | Kentucky: +8.5 (-110)
• Total: 51.5 -- Over: (-118) | Under: (-104)

LSU vs Kentucky Betting Trends

• LSU has won twice against the spread this year.
• LSU has two wins ATS (2-2) as an 8.5-point or higher favorite in 2026.
• There have been three LSU games (of five) that hit the over this year.
• Kentucky has four wins in five contests against the spread this year.
• Kentucky has one win ATS (1-1) as an 8.5-point underdog or more this year.
• This season, four of Kentucky's five games have hit the over.

LSU vs Kentucky Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (66.9%)

LSU vs Kentucky Point Spread

Kentucky is an underdog by 8.5 points versus LSU. Kentucky is -110 to cover the spread, and LSU is -110.

LSU vs Kentucky Over/Under

LSU versus Kentucky on Oct. 10 has an over/under of 51.5 points, with the over -118 and the under -104.

LSU vs Kentucky Moneyline

The moneyline numbers for LSU vs. Kentucky reveal LSU as the favorite (-334) and Kentucky as the underdog (+265).

LSU vs. Kentucky Points Insights

LSU vs. Kentucky Game Info

• Game day: Saturday, October 10, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN
• Location: Lexington, Kentucky
• Stadium: Kroger Field

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Check out even more in-depth LSU vs. Kentucky analysis on FanDuel Research.