Cowboys vs Bucs Prediction, Odds, Picks, Best Bets for NFL Week 5 Thursday Night Football

Cowboys vs Bucs TNF Prop Bets at a Glance

• Jalon Daniels 50+ Rushing Yards (+104)
• George Pickens Anytime Touchdown (+120)
• George Pickens 60+ Receiving Yards (-128)

Week 5 kicks off with the Tampa Bay Buccaneers visiting the Dallas Cowboys on Thursday Night Football.

Dallas enters the matchup with one of the more dangerous passing attacks in the league while Tampa Bay will once again ask rookie Jalon Daniels to keep the offense moving with Baker Mayfield sidelined. Daniels flashed some rushing upside in his first NFL start, but this is a difficult assignment on the road against a Cowboys team capable of putting points on the board quickly.

Using the NFL odds at FanDuel Sportsbook, let’s break down my favorite Buccaneers-Cowboys picks and props for TNF.

All NFL projections via our numbers at FanDuel Research, and NFL odds come from FanDuel Sportsbook. Lines may change after this article is published.

Take advantage of our Thursday Night Football Promo!

YOU CAN CHOOSE between a 50% Profit Boost Token OR an Up-7 Early Win Token to use on the Buccaneers at Cowboys NFL game on October 8th, 2026! See here for full terms and conditions.

Learn about today's other offers at FanDuel Sportsbook Promos.

Cowboys vs Bucs Prop Bets, NFL Picks for TNF

Jalon Daniels 50+ Rushing Yards (+104)

In his NFL debut, Jalon Daniels was excellent as a runner, and I think this game sets up well for him to scramble a lot.

Daniels ran it eight times for 55 yards last week. He struggled through the air (148 passing yards), but given that he’s an undrafted rookie who was forced into a start this early in the season, Daniels did a serviceable job overall.

The Dallas Cowboys‘ defense is really struggling, and they’ve allowed the most rushing yards per game to QBs (47.0). As an added bonus, the Tampa Bay Buccaneers are 8.5-point road ‘dogs. That should set up a game script that leads to plenty of Daniels’ drop backs, which means more chances to scramble.

Fifty yards is a high bar to clear for any QB, but Daniels is an explosive runner in a matchup where he should be able to show off his running prowess.

George Pickens Anytime Touchdown (+120)

George Pickens 60+ Receiving Yards (-128)

CeeDee Lamb has been unbelievable so far this year, running as Dallas’ clear WR1 over George Pickens, who has yet to score a TD this season. I can see that changing on TNF.

Through four weeks, Lamb has 46 targets to Pickens’ 28 as well as 498 yards to Pickens’ 225. While Lamb is a monster, I think there’s some small-sample noise at play. A year ago, Pickens actually had more catches per game (5.5 to 5.4) and receiving yards per game (84.1 to 76.9) than Lamb did.

The market expects Dallas to be able to move the ball really well, listing the Cowboys at -111 odds to go over 29.5 points. Pickens is due for a big game, and with his big-play ability, he’s capable of ripping off a chunk gain on any grab.

I like him to find the end zone against the Bucs, and I’m also backing Pickens to go for at least 60 receiving yards.

NFL Betting Frequently Asked Questions

What is an NFL point spread?

A point spread is designed to level the playing field between two teams. Favorites must win by more than the spread, while underdogs can either win outright or lose by fewer points than the spread.

What is an NFL moneyline bet?

A moneyline bet is simply picking which team will win the game. Favorites have negative odds, while underdogs have positive odds.

What are NFL player props?

Player prop bets focus on an individual player's performance, such as passing yards, rushing yards, receiving yards, touchdowns, or receptions, rather than the outcome of the game.

Which NFL bets stand out to you? Check out FanDuel Sportsbook's latest NFL odds to see the full menu of options.

You can also check out our How to Bet on the NFL guide.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.