Knicks vs. Celtics Eastern Semifinals Prediction, Odds, Picks, Best Bets for May 16

Knicks vs. Celtics Game Info

• Date: Friday, May 16, 2025
• Time: 8 p.m. ET
• Venue: Madison Square Garden -- New York City, New York
• Coverage: ESPN

The New York Knicks are slight 2.5-point favorites heading into a decisive Game 6 of the second round of the NBA Playoffs against the Boston Celtics at Madison Square Garden on Friday, starting at 8 p.m. ET on ESPN. The Knicks have a 3-2 lead in the series. The point total is set at 210 for the matchup.

Knicks vs. Celtics Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Knicks vs. Celtics Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Knicks win (52.6%)

Knicks vs. Celtics Betting Trends

• The Knicks have put together a record of 40-41-1 against the spread this season.
• In the Celtics' 82 games this season, they have 39 wins against the spread.
• Knicks games have finished with a final combined score above the over/under 43 times this season.
• Celtics games this year have hit the over on 37 of 82 set point totals (45.1%).
• New York has covered the spread in a higher percentage of its home games than road games. It has covered 21 times in 41 opportunities at home, and it has covered 19 times in 41 opportunities in road games.
• The Knicks have gone over the total more consistently at home, hitting the over in 23 of 41 home matchups (56.1%). In road games, they have hit the over in 20 of 41 games (48.8%).
• Boston's winning percentage against the spread at home is .439 (18-23-0). On the road, it is .512 (21-19-1).
• In terms of the over/under, Celtics games have finished over 21 of 41 times at home (51.2%), and 16 of 41 on the road (39%).

Knicks Leaders

• Karl-Anthony Towns is averaging 24.4 points, 12.8 boards and 3.1 assists. Defensively, he averages 1 steal and 0.7 blocked shots.
• Josh Hart is averaging 13.6 points, 9.6 boards and 5.9 assists. At the other end, he averages 1.5 steals (ninth in league) and 0.4 blocked shots.
• Jalen Brunson is averaging 26 points, 7.3 assists and 2.9 rebounds.
• Mikal Bridges is averaging 17.6 points, 3.2 rebounds and 3.7 assists.
• OG Anunoby's numbers on the season are 18 points, 4.8 rebounds and 2.2 assists per game, shooting 47.6% from the floor and 37.2% from beyond the arc, with an average of 2.3 made 3-pointers.

Celtics Leaders

• Per game, Derrick White gets the Celtics 16.4 points, 4.5 rebounds and 4.8 assists. He also averages 0.9 steals and 1.1 blocks.
• Jaylen Brown averages 22.2 points, 5.8 rebounds and 4.5 assists. He is also draining 46.3% of his shots from the field and 32.4% from 3-point range, with 1.8 triples per contest.
• The Celtics get 14.3 points per game from Payton Pritchard, plus 3.8 boards and 3.5 assists.
• The Celtics are receiving 11.1 points, 4.3 rebounds and 3.9 assists per game from Jrue Holiday.
• Kristaps Porzingis' numbers on the season are 19.5 points, 6.8 rebounds and 2.1 assists per contest. He is draining 48.3% of his shots from the floor and 41.2% from beyond the arc, with an average of 2.5 treys.

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