Knicks vs. Cavaliers Prediction, Odds, Picks, Best Bets for Nov. 11

Knicks vs. Cavaliers Game Info

• Date: Wednesday, November 11, 2026
• Time: 7 p.m. ET
• Venue: Madison Square Garden -- New York City, New York
• Coverage: ESPN, MSG, and DAZN-MSG

The New York Knicks (6-4) are favored (by 4.5 points) to continue a four-game home winning streak when they host the Cleveland Cavaliers (5-6) on Wednesday, November 11, 2026 at 7 p.m. ET. The matchup's point total is set at 221.5.

Knicks vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Knicks vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Knicks win (56.5%)

Knicks vs. Cavaliers Betting Trends

• The Knicks have compiled a 4-6-0 record against the spread this season.
• In the Cavaliers' 11 games this season, they have three wins against the spread.
• Games involving the Knicks have hit the over twice out of 11 chances this season.
• Cavaliers games this year have hit the over on five of 11 set point totals (45.5%).
• Against the spread, New York has played better when playing at home, covering three times in six home games, and one time in four road games.
• The Knicks have hit the over on the over/under in a lower percentage of home games (16.7%) than away games (25%).
• This year, Cleveland is 2-4-0 at home against the spread (.333 winning percentage). Away, it is 1-4-0 ATS (.200).
• Cavaliers games have gone above the over/under less often at home (two times out of six) than on the road (three of five) this year.

Knicks Leaders

• Karl-Anthony Towns averages 20.9 points, 13.8 rebounds and 3.1 assists, shooting 54.3% from the field and 39.6% from beyond the arc, with 1.9 made 3-pointers per game.
• Jalen Brunson is averaging 25.9 points, 3.1 boards and 5.2 assists. Defensively, he averages 0.6 steals and 0.3 blocked shots.
• OG Anunoby is averaging 16.7 points, 2.4 assists and 5.3 boards.
• Andre Drummond is averaging 4.7 points, 1.2 assists and 8.4 boards.
• Mikal Bridges averages 6.3 points, 3.4 rebounds and 2.1 assists, shooting 32.9% from the field.

Cavaliers Leaders

• Donovan Mitchell averages 22.8 points for the Cavaliers, plus 4.8 boards and 5.5 assists.
• The Cavaliers are receiving 17.5 points, 7.5 rebounds and 3.6 assists per game from Evan Mobley.
• The Cavaliers get 15.3 points per game from James Harden, plus 4.8 rebounds and 5.7 assists.
• Per game, Jarrett Allen gets the Cavaliers 13.1 points, 7.7 boards and 1.2 assists, plus 0.6 steals and 1.4 blocks (eighth in NBA).
• Peyton Watson's numbers on the season are 11.4 points, 4.6 boards and 2.7 assists per contest. He is draining 40.6% of his shots from the floor.

For more NBA betting insights, check out FanDuel Research's NBA home page.

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