Kansas vs West Virginia Prediction, Odds, Picks, Best Bets for Week 4 2025

The Kansas Jayhawks are among the college football teams busy on Saturday, versus the West Virginia Mountaineers.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Kansas vs West Virginia Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Kansas: (-490) | West Virginia: (+365)
• Spread: Kansas: -13.5 (-112) | West Virginia: +13.5 (-108)
• Total: 55.5 -- Over: (-108) | Under: (-112)

Kansas vs West Virginia Betting Trends

• Kansas has posted one win against the spread this season.
• As a 13.5-point or greater favorite, Kansas has one win ATS (1-1) this season.
• One of Kansas' three games this season has gone over the point total.
• West Virginia owns two wins against the spread this season.
• None of West Virginia's three games has gone over the point total in 2025.

Kansas vs West Virginia Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Jayhawks win (77.1%)

Kansas vs West Virginia Point Spread

West Virginia is listed as an underdog by 13.5 points (-108 odds), and Kansas, the favorite, is -112 to cover.

Kansas vs West Virginia Over/Under

An over/under of 55.5 has been set for Kansas-West Virginia on Sept. 20, with the over being -108 and the under -112.

Kansas vs West Virginia Moneyline

The moneyline numbers for Kansas vs. West Virginia reveal Kansas as the favorite (-490) and West Virginia as the underdog (+365).

Kansas vs. West Virginia Points Insights

Kansas vs. West Virginia Game Info

• Game day: Saturday, September 20, 2025
• Game time: 6 p.m. ET
• TV channel: Fox Sports 1
• Location: Lawrence, Kansas
• Stadium: David Booth Kansas Memorial Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Kansas vs. West Virginia analysis on FanDuel Research.