Jonathan Taylor Fantasy Football Week 16: Stats and Projections vs. 49ers

In Week 16 (Monday at 8:15 p.m. ET), running back Jonathan Taylor and the Indianapolis Colts will face the San Francisco 49ers, who have the 12th-ranked rushing defense in the league (106.1 yards allowed per game).

For more info on Taylor, if you're thinking about him for your daily fantasy lineup, scroll down before his upcoming game against the 49ers.

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Jonathan Taylor Week 16 Fantasy Football Projection

• Matchup: Indianapolis Colts vs. San Francisco 49ers
• Game Date: December 22, 2025
• Game Time: 8:15 p.m.
• Projected Fantasy Points: 18.9
• PPR Projected Fantasy Points: 21.0
• Projected Rushing Yards: 105.46
• Projected Rushing TDs: 0.91
• Projected Receiving Yards: 21.63
• Projected Receiving TDs: 0.15

Projections provided by numberFire

Taylor Fantasy Performance

• Taylor is currently the top fantasy player at his position (eighth overall), piling up 284.1 fantasy points (20.3 per game).
• In his last three games, Taylor has posted 33.6 fantasy points (11.2 per game), running for 246 yards and scoring one touchdown on 67 carries. He has also helped out in the passing game with 50 yards on six grabs (nine targets) as a pass-catcher.
• Taylor has delivered 86.8 total fantasy points (17.4 per game) during his last five games, running the ball 115 times for 548 yards and four scores. In the receiving game, he has tacked on 100 yards on 11 receptions (15 targets).
• The high point of Taylor's fantasy season came against the Atlanta Falcons in Week 10, when he put up 46.6 fantasy points with three receptions (on three targets) for 42 yards.
• From a fantasy perspective, Jonathan Taylor's matchup versus the Pittsburgh Steelers in Week 9 was his worst of the year, as he put up just 5.7 fantasy points. He ran for 45 yards on 14 carries on the day with two catches for 12 yards.

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49ers Defensive Performance

• San Francisco has allowed three players to rack up more than 300 yards passing in a game this season.
• The 49ers have allowed 13 players to pass for at least one TD in a game this season.
• A total of eight players have thrown for at least two TDs against San Francisco this season.
• The 49ers have allowed three or more passing TDs to three opposing QBs this season.
• A total of three players have recorded over 100 yards receiving in a game versus San Francisco this year.
• A total of 24 players have hauled in a TD pass versus the 49ers this season.
• San Francisco has allowed two or more receiving touchdowns to only one player this year.
• The 49ers have allowed only two players to rack up over 100 yards rushing in a game this year.
• San Francisco has given up at least one rushing TD to eight players this year.
• Just one player has run for more than one TD against the 49ers this year.

Want more data and analysis on Jonathan Taylor? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.