Houston vs Colorado Prediction, Odds, Picks, Best Bets for Week 11 2026

The college football slate on Friday includes the Houston Cougars taking on the Colorado Buffaloes.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Houston vs Colorado Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Houston: (-385) | Colorado: (+310)
• Spread: Houston: -10.5 (100) | Colorado: +10.5 (-120)
• Total: 51.5 -- Over: (-105) | Under: (-115)

Houston vs Colorado Betting Trends

• Houston has three wins in nine games against the spread this season.
• As a 10.5-point or greater favorite, Houston has one win ATS (1-4) this season.
• This season, five of Houston's nine games have hit the over.
• Against the spread, Colorado is 3-6-0 this year.
• Colorado has won once ATS (1-2) as a 10.5-point underdog or greater this year.
• Of nine Colorado games so far this year, four have gone over the total.

Houston vs Colorado Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (83.5%)

Houston vs Colorado Point Spread

Colorado is listed as an underdog by 10.5 points (-120 odds), and Houston, the favorite, is +100 to cover.

Houston vs Colorado Over/Under

The over/under for Houston-Colorado on Nov. 13 is 51.5. The over is -105, and the under is -115.

Houston vs Colorado Moneyline

Looking at the moneyline for Houston-Colorado, Houston is the favorite at -385, and Colorado is +310.

Houston vs. Colorado Points Insights

Houston vs. Colorado Game Info

• Game day: Friday, November 13, 2026
• Game time: 10:15 p.m. ET
• TV channel: ESPN
• Location: Boulder, Colorado
• Stadium: Folsom Field

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Check out even more in-depth Houston vs. Colorado analysis on FanDuel Research.