Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 24

Odds updated as of 9:12 p.m.

In MLB action on Wednesday, the Cleveland Guardians play the Chicago White Sox.

We've got you covered, in terms of the vital info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs White Sox Game Info

• Cleveland Guardians (41-38) vs. Chicago White Sox (40-37)
• Date: Wednesday, June 24, 2026
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CleGuardians.TV

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-118) | CHW: (+100)
• Spread: CLE: -1.5 (+134) | CHW: +1.5 (-162)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 2-8, 4.03 ERA vs Erick Fedde (White Sox) - 2-6, 4.46 ERA

The Guardians will give the nod to Tanner Bibee (2-8, 4.03 ERA), who is eyeing win No. 3 on the season, and the White Sox will turn to Erick Fedde (2-6, 4.46 ERA). Bibee's team is 3-12-0 against the spread in his starts this season. Bibee's team has a record of 2-7 this season when he starts and they are the favorite on the moneyline. The White Sox have gone 5-3-0 against the spread when Fedde starts. The White Sox are 4-4 in Fedde's eight starts this season that they were the underdog on the moneyline.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (53%)

Guardians vs White Sox Moneyline

• Chicago is the underdog, +100 on the moneyline, while Cleveland is a -118 favorite despite being on the road.

Guardians vs White Sox Spread

• The White Sox are +1.5 on the spread (-162 to cover), and Cleveland is +134 to cover the runline.

Guardians vs White Sox Over/Under

• Guardians versus White Sox, on June 24, has an over/under of 8.5, with the over being -115 and the under -105.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have been favorites in 39 games this season and have come away with the win 20 times (51.3%) in those contests.
• Cleveland has a record of 18-16 in contests when oddsmakers favor them by -118 or more on the moneyline.
• The Guardians and their opponents have gone over in 38 of their 75 games with a total set by sportsbooks this season.
• The Guardians have posted a record of 39-36-0 against the spread this season.
• The White Sox have a 31-33 record in games they were listed as the moneyline underdog (winning 48.4% of those games).
• Chicago is 26-29 (winning 47.3% of its games) when playing as a moneyline underdog of +100 or longer.
• The White Sox have played in 75 games with an over/under set, and have combined with opponents to go over the total 43 times (43-31-1).
• The White Sox have a 43-32-0 record ATS this season (covering 57.3% of the time).

Guardians Player Leaders

• Brayan Rocchio leads Cleveland with an OBP of .351, plus a team-best slugging percentage of .398. He's batting .275 on the season.
• Among qualified hitters in the majors, his batting average ranks 42nd, his on-base percentage ranks 49th, and he is 102nd in slugging.
• Rocchio hopes to build on a two-game hitting streak in this matchup. During his last five outings he is hitting .381 with three doubles, a walk and an RBI.
• Travis Bazzana is batting .274 with 11 doubles, a triple, seven home runs and 26 walks. He's slugging .469 with an on-base percentage of .373.
• Bazzana takes a six-game streak with at least one hit into this contest. In his last 10 outings he is batting .353 with two doubles, three home runs, eight walks and seven RBIs.
• Steven Kwan is batting .206 with a .251 slugging percentage and 13 RBI this year.
• Kyle Manzardo has been key for Cleveland with 50 hits, an OBP of .324 plus a slugging percentage of .404.

White Sox Player Leaders

• Miguel Vargas is hitting .236 with 12 doubles, a triple, 16 home runs and 45 walks. He's slugging .462 with an on-base percentage of .352.
• Including all qualified players in the majors, he is 110th in batting average, 48th in on-base percentage and 51st in slugging percentage.
• Colson Montgomery has 13 doubles, 20 home runs and 28 walks while batting .218. He's slugging .487 with an on-base percentage of .312.
• Including all qualified hitters, he ranks 142nd in batting average, 111th in on-base percentage and 31st in slugging percentage.
• Sam Antonacci is hitting .291 with 10 doubles, two triples, four home runs and 17 walks.
• Chase Meidroth is slugging .384 to pace his team.

Guardians vs White Sox Head to Head

• 6/22/2026: 6-5 CHW (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/14/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2025: 3-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/12/2025: 4-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/10/2025: 6-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/9/2025: 3-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/8/2025: 9-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/13/2025: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/11/2025: 5-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!