Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 8

Odds updated as of 4:19 p.m.

The Cleveland Guardians will take on the Chicago White Sox in MLB action on Tuesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this game.

Guardians vs White Sox Game Info

• Cleveland Guardians (3-6) vs. Chicago White Sox (2-7)
• Date: Tuesday, April 8, 2025
• Time: 4:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and CHSN+

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-190) | CHW: (+160)
• Spread: CLE: -1.5 (+115) | CHW: +1.5 (-138)
• Total: 7 -- Over: (-122) | Under: (-100)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Ben Lively (Guardians) - 0-1, 6.75 ERA vs Shane Smith (White Sox) - 0-0, 3.18 ERA

The Guardians will give the ball to Ben Lively (0-1, 6.75 ERA), who is eyeing win No. 1 on the season, and the White Sox will turn to Shane Smith. Lively has a record of 1-1-0 ATS in two starts with a spread this season. Lively has yet to start a game this season when his team was the moneyline favorite. Smith has started only one game with a set spread, which the White Sox failed to cover. The White Sox were the underdog on the moneyline for one Smith start this season -- they lost.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (60.6%)

Guardians vs White Sox Moneyline

• Chicago is the underdog, +160 on the moneyline, while Cleveland is a -190 favorite at home.

Guardians vs White Sox Spread

• The Guardians are hosting the White Sox and are favored by 1.5 runs (+115 to cover) on the runline. Chicago is -138 to cover.

Guardians vs White Sox Over/Under

• The Guardians-White Sox contest on April 8 has been given an over/under of 7 runs. The over is set at -122 and the under at -100.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have been favorites in three games this season and have come away with the win one time (33.3%) in those contests.
• These are the best odds of a victory sportsbooks have given Cleveland this season, with a -190 moneyline set for this game.
• Contests with the Guardians have gone over the total set by oddsmakers in five of nine chances this season.
• The Guardians are 3-6-0 against the spread in their nine games with a line set by sportsbooks this season.
• The White Sox have won two of the nine games they were the underdog on the moneyline this season (22.2%).
• Chicago has played as a moneyline underdog of +160 or longer in only two games this season, which it lost both.
• The White Sox have played in nine games with a set over/under, and have combined with opponents to go over the total five times (5-3-1).
• The White Sox have a 5-4-0 record ATS this season (covering 55.6% of the time).

Guardians Player Leaders

• Jose Ramirez leads Cleveland with eight hits and an OBP of .438 this season. He has a .320 batting average and a slugging percentage of .880.
• Among qualifying hitters in baseball, he is 32nd in batting average, 14th in on-base percentage, and first in slugging.
• Kyle Manzardo is hitting .258 with a double, a triple, three home runs and four walks. He's slugging .645 with an on-base percentage of .324.
• Among all qualified hitters, he is 78th in batting average, 90th in on-base percentage and 13th in slugging percentage.
• Manzardo heads into this matchup looking to extend his three-game hit streak. During his last five outings he is hitting .167 with a home run, a walk and three RBI.
• Steven Kwan has hit one homer with a team-high .471 SLG this season.
• Kwan enters this matchup with five games in a row with at least one hit. During his last five outings he is hitting .333 with two walks.
• Carlos Santana has one home run, three RBI and a batting average of .265 this season.

White Sox Player Leaders

• Andrew Benintendi has an on-base percentage of .333, a slugging percentage of .484, and has nine hits, all club-bests for the White Sox (while batting .290).
• Including all qualified hitters in the big leagues, he ranks 45th in batting average, 75th in on-base percentage and 57th in slugging percentage.
• Nick Maton has two home runs and four walks while batting .150. He's slugging .450 with an on-base percentage of .292.
• Matt Thaiss is hitting .250 with a double and five walks.
• Brooks Baldwin is hitting .280 with a double and a home run.

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